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To date, knowledge of the longitudinal psychosocial response to the diagnosis of human papillomavirus is limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A prospective longitudinal design was conducted with a convenience sample.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Women aged 20\u201365\u00a0years old were followed at one, 6 and 12\u00a0months after a diagnosis of <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>. Participants completed measures of initial emotional distress and followed up psychosocial adjustment. A mixed\u2010effects model was applied to analyse the longitudinal changes in psychosocial adjustment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy human papillomavirus positive women participated in the study with nearly 20% of the women reporting emotional distress during their first visit. Mixed\u2010effects model analyses showed that a trajectory of psychosocial adjustment in healthcare orientation, sexual relationship and psychosocial distress occur from one to 6\u00a0months after <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> diagnosis. However, a declining trend from 6 to 12\u00a0months was significant in healthcare orientation. Initial emotional distress was associated with changes in psychological adjustment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Psychosocial adjustment to human papillomavirus was worse at 1\u00a0month compared with 6 and 12\u00a0months after diagnosis. Healthcare providers should offer health information and psychosocial support to women according to their disease progression.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jan.13725","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T01:34:27Z","timestamp":1527644067000},"page":"2523-2532","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Longitudinal psychosocial adjustment of women to human papillomavirus infection"],"prefix":"10.1111","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6426-1021","authenticated-orcid":false,"given":"Yu\u2010Yun","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Nursing College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Ming","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Statistics College of Management National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan Jane","family":"Fetzer","sequence":"additional","affiliation":[{"name":"College of Health and Human Services University of New Hampshire Durham NH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u2010Min","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology National Cheng Kung University Hospital College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keng\u2010Fu","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology National Cheng Kung University Hospital College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2011.05693.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.54.5.248"},{"issue":"3","key":"e_1_2_10_4_1","first-page":"Cd008054","article-title":"Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions","author":"Arbyn M.","year":"2013","journal-title":"The Cochrane Database of Systematic Reviews"},{"key":"e_1_2_10_5_1","first-page":"379","article-title":"HPV prevalence at enrollment and baseline results from the Carolina Women's Care Study, a longitudinal study of HPV persistence in women of college age","volume":"5","author":"Banister C. 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