{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:16:08Z","timestamp":1791418568315,"version":"4.3.3"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T00:00:00Z","timestamp":1603065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To assess the prevalence and associated factors of psychological distress among patients with chronic hepatitis B receiving oral antiviral therapy and explore the association between psychological distress and self\u2010management behaviours among this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A convenience sample of 188 patients with chronic hepatitis B receiving oral antiviral therapy was recruited from March\u2010October 2018 to complete a self\u2010report questionnaire including the Chinese version of Depression Anxiety Stress Scale\u201021 and Chronic Hepatitis B Self\u2010Management Scale. Logistic regression analysis and hierarchical multiple regression analysis were used to determine the factors associated with psychological distress and the association between psychological distress and self\u2010management behaviours respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of depression, anxiety, and stress symptoms were 33.0%, 38.3% and 17.6% respectively. Depression was associated with older age, female gender, lower education level and longer treatment duration; anxiety was associated with female gender and longer treatment duration; and stress was associated with age of 31\u201340\u00a0years, female gender and unmarried status. There were significant associations between depression and anxiety symptoms and self\u2010management behaviours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Psychological distress was prevalent among patients with chronic hepatitis B receiving oral antiviral therapy and had a negative impact on self\u2010management. Interventions targeting depression and anxiety symptoms may be beneficial to improve self\u2010management behaviours for this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Impact<\/jats:title><jats:p>This study explored the factors associated with psychological distress in patients with chronic hepatitis B receiving oral antiviral therapy. The findings showed psychological distress was more common in patients who were with older age, female, less educated, unmarried and receiving longer duration of treatment and psychological distress was significantly associated with self\u2010management behaviours. Nurses and other healthcare providers should provide interventions to reduce the risk of psychological distress and improve self\u2010management behaviours for this population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jan.14610","type":"journal-article","created":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T18:14:00Z","timestamp":1603131240000},"page":"266-274","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Psychological distress and self\u2010management behaviours among patients with chronic hepatitis B receiving oral antiviral therapy"],"prefix":"10.1111","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4612-5389","authenticated-orcid":false,"given":"Ling\u2010Na","family":"Kong","sequence":"first","affiliation":[{"name":"School of Nursing The First Affiliated Hospital of Chongqing Medical University Chongqing PR China"},{"name":"School of Nursing Chongqing Medical University Chongqing PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Nursing Chongqing Medical and Pharmaceutical College Chongqing PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of liver disease Chongqing Hospital of Traditional Chinese Medicine Chongqing PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3115-3128","authenticated-orcid":false,"given":"Qing\u2010Hua","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Nursing The First Affiliated Hospital of Chongqing Medical University Chongqing PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of infectious disease The First Affiliated Hospital of Chongqing Medical University Chongqing PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Lan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of infectious disease The First Affiliated Hospital of Chongqing Medical University Chongqing PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajp.2015.10.004"},{"key":"e_1_2_9_3_1","first-page":"160","article-title":"Psychiatric morbidity in Chinese patients with chronic hepatitis B infection in a local infectious disease clinic","volume":"22","author":"Chan H.","year":"2012","journal-title":"East Asian Archives of Psychiatry"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1474515116687179"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40615-018-0500-3"},{"key":"e_1_2_9_6_1","volume-title":"Statistical power for the behavioral sciences","author":"Cohen J.","year":"1988"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175096"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2018.03.006"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1054773812436681"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2014.302041"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2018.12.001"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2014.58"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13168"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2011.13.1\/wkaton"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-14-69"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/SGA.0b013e3182a788cc"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0134125"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apnr.2018.03.009"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2019.06.013"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfp155"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.14973"},{"key":"e_1_2_9_22_1","first-page":"64","article-title":"Investigation and analysis of self\u2010management of patients with chronic hepatitis B","volume":"7","author":"Lin Z. X.","year":"2015","journal-title":"Chinese Journal of Liver Diseases (Electronic Version)"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-7967(94)00075-U"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6160927"},{"key":"e_1_2_9_25_1","first-page":"114","article-title":"A review of psychosocial issues in patients with chronic hepatitis B","volume":"16","author":"Modabbernia A.","year":"2013","journal-title":"Archives of Iranian Medicine"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/1474515117722255"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnu.12464"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANS.0000000000000237"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANS.0b013e318261b1ba"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-014-9580-2"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28156"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-2917"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16020255"},{"key":"e_1_2_9_34_1","volume-title":"Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection","author":"World Health Organization","year":"2015"},{"key":"e_1_2_9_35_1","first-page":"1436","article-title":"Psychometric properties of the Chinese Short Version of Depression Anxiety and Stress Scale in Chinese adults","volume":"28","author":"Wen Y.","year":"2012","journal-title":"Chinese Journal of Public Health"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/16549716.2018.1433987"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijn.12031"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003779"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2016.3271"}],"container-title":["Journal of Advanced Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jan.14610","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jan.14610","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jan.14610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T19:35:01Z","timestamp":1693683301000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jan.14610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,19]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/jan.14610"],"URL":"https:\/\/doi.org\/10.1111\/jan.14610","archive":["Portico"],"relation":{},"ISSN":["0309-2402","1365-2648"],"issn-type":[{"value":"0309-2402","type":"print"},{"value":"1365-2648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,19]]},"assertion":[{"value":"2020-02-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}