{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T06:37:11Z","timestamp":1787899031287,"version":"build-2784847793"},"reference-count":66,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["71774178"],"award-info":[{"award-number":["71774178"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012245","name":"Science and Technology Planning Project of Guangdong Province","doi-asserted-by":"publisher","award":["2017A020212006"],"award-info":[{"award-number":["2017A020212006"]}],"id":[{"id":"10.13039\/501100012245","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aimed to explore the mediating effect of self\u2010management (SM) on the relationship between illness perception and quality of life (QOL) among Human immunodeficiency virus (HIV)\u2010positive men who have sex with men (MSM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A cross\u2010sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We explored the effect of illness perception and self\u2010management on QOL using the multiple regression model. Moreover, we conducted a simple mediation analysis to examine the role of SM in the relationship between illness perception and QOL. In addition, a parallel mediation analysis was performed to investigate the differences in domains of SM on the relationship between illness perception and QOL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 300 Chinese HIV\u2010positive MSM, the mean score of SM was 39.9\u2009\u00b1\u20096.97, with a range of 14.0\u201354.0. The higher score in SM indicated a higher level of HIV SM. SM was negatively related to illness perception (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009\u22120.47) while positively related to QOL (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.56). SM partially mediated the relationship between illness perception and QOL, accounting for 25.3% of the total effect. Specifically, both daily self\u2010management health practices and the chronic nature of the self\u2010management domain played a parallel role in mediating the relationship between illness perception and QOL.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study demonstrated that SM was a significant factor influencing QOL among HIV\u2010positive MSM. Focusing on daily self\u2010management health practices and the chronic nature of self\u2010management could be the potential key targets for enhancing HIV self\u2010management strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for the Profession and\/or Patient Care<\/jats:title>\n                    <jats:p>This study emphasized the role of SM in the well\u2010being of HIV\u2010positive MSM and underscored the importance of developing interventions that integrate SM strategies to improve QOL in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>No patient or public contribution.<\/jats:p>\n                  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