{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:43:34Z","timestamp":1793321014974,"version":"4.5.0"},"reference-count":84,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T00:00:00Z","timestamp":1734220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFE0206600"],"award-info":[{"award-number":["2021YFE0206600"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001547","name":"China Medical Board","doi-asserted-by":"publisher","award":["22\u2010482"],"award-info":[{"award-number":["22\u2010482"]}],"id":[{"id":"10.13039\/100001547","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To systematically identify, describe and evaluate the existing risk prediction models for cancer\u2010related fatigue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>Seven databases (EMBASE, Cochrane Database, MEDLINE, CINAHL, CNKI, SinoMed and Wanfang) were conducted from inception to August 14, 2023 and updated in September 15, 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>A systematic search was conducted to identify studies that reported the development of risk prediction models for cancer\u2010related fatigue. Two researchers independently performed a comprehensive assessment of the included studies. The Prediction Model Risk of Bias Assessment Tool was used to assess the risk of bias and applicability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighteen studies were included in this review. These models predicted cancer\u2010related fatigue in various cancers, including breast cancer, prostate cancer, gynaecological tumours and lung cancer. The most commonly included predictors were anxiety and depression, age, chemotherapy status, sleep quality and pain. Thirteen studies assessed the model performance by using the receiver operating characteristic curve. Although most models exhibited good predictive performance, a higher risk of bias was observed because of inappropriate handling of missing data methods and an imbalance in events per variable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Prediction models show promise for cancer\u2010related fatigue management and precision care, but few are ready for clinical application due to methodological limitations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for the Profession<\/jats:title>\n                    <jats:p>Future research should focus on improving the clinical utility of cancer\u2010related fatigue models while balancing predictive accuracy with cost\u2010effectiveness to promote equitable care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>This study critically systematically evaluated the prediction models of cancer\u2010related fatigue. The existing prediction models have a weak methodological foundation, with only a few having the potential to be implemented in clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Reporting Method<\/jats:title>\n                    <jats:p>The review is reported using the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) guidelines and the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis in Systematic Reviews and Meta\u2010Analyses checklist (TRIPOD\u2010SRMA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Public Contribution<\/jats:title>\n                    <jats:p>No patient or public contribution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jan.16680","type":"journal-article","created":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T23:30:11Z","timestamp":1734305411000},"page":"4465-4484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Risk Prediction Models as an Emerging Trend for Managing Cancer\u2010Related Fatigue: A Systematic Review"],"prefix":"10.1111","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5780-9033","authenticated-orcid":false,"given":"Yun","family":"Zhang","sequence":"first","affiliation":[{"name":"West China School of Nursing, Sichuan University\/Department of Nursing, West China Hospital Sichuan University  Chengdu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linna","family":"Li","sequence":"additional","affiliation":[{"name":"West China School of Nursing, Sichuan University\/Department of Nursing, West China Hospital Sichuan University  Chengdu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Li","sequence":"additional","affiliation":[{"name":"General Practice Medical Center, West China Hospital Sichuan University  Chengdu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Zhang","sequence":"additional","affiliation":[{"name":"West China School of Nursing, Sichuan University\/Department of Nursing, West China Hospital Sichuan University  Chengdu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhou","sequence":"additional","affiliation":[{"name":"West China School of Nursing, Sichuan University\/Department of Nursing, West China Hospital Sichuan University  Chengdu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5815-021X","authenticated-orcid":false,"given":"Xiaoli","family":"Chen","sequence":"additional","affiliation":[{"name":"West China School of Nursing, Sichuan University\/Department of Nursing, West China Hospital Sichuan University  Chengdu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Hu","sequence":"additional","affiliation":[{"name":"West China School of Nursing, Sichuan University\/Department of Nursing, West China Hospital Sichuan University  Chengdu People's Republic of China"},{"name":"Tianfu Jincheng Laboratory City of Future Medicine  Chengdu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw099"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.12126"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc4029"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/s23218694"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010023\u201001491\u20101"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2015.0122"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2022.05.001"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l737"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2014.127"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.53.4495"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1188\/15.CJON.137\u2010139"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2013.07.050"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010021\u201008831\u20103"},{"issue":"9","key":"e_1_2_11_15_1","first-page":"11","article-title":"Establishment of a Nomogram Model for Individualized Prediction of Cancer\u2010Related Fatigue in Prostate Cancer Patients","volume":"61","author":"Chen X.","year":"2023","journal-title":"China Modern Doctor"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12912\u2010023\u201001363\u20100"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14\u20100697"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn115682\u201020220523\u201002457"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2012.10.002"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2022.07.019"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2020.103611"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i6460"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01252"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v11.i9.705"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010022\u201007570\u2010w"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)00242\u20102"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2017.04.012"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2023.104623"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40780\u2010023\u201000275\u20100"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0032844"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010013\u20101897\u20101"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753495X20984015"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.11.143"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010021\u201009072\u20100"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0000000000000862"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2019.12.007"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010023\u201007892\u20103"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010022\u201007432\u20105"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocz228"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.19791\/j.cnki.1006\u20106411.2022.25.037"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4238"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.12.9791"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyz274"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41512\u2010020\u201000090\u20103"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41512\u2010018\u20100045\u20102"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010015\u20100450\u20102"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010023\u201039046\u20100"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0267931"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2007.06.001"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010023\u201007723\u20105"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/21641846.2021.1885119"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2012.196"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkaa039"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2023.104588"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3115"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2020.103707"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2020.07.037"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010019\u201000767\u20109"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010022\u201001528\u20104"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14\u20100698"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001744"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.7326\/M18\u20101377"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010180199"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k1415"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwaa124"},{"issue":"11","key":"e_1_2_11_67_1","first-page":"808","article-title":"Strategies for Addressing Cancer Patients' Complaints of Fatigue","volume":"31","author":"Saiki C. B.","year":"2017","journal-title":"Oncology\u2010New York"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432\u2010023\u201005197\u2010w"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2014.09.007"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14081982"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj\u20102022\u2010073538"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432\u2010022\u201004161\u20104"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-16399-0_5"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu207"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010021\u201011294\u20102"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15072181"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4076"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2017.1557"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.12182\/20230760507"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1674\u20104721.2023.17.003"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.19381\/j.issn.1001\u20107585.2023.02.005"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010020\u201005483\u20100"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn211501\u201020210726\u201002115"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.16872"}],"container-title":["Journal of Advanced Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jan.16680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:01:46Z","timestamp":1762524106000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jan.16680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,15]]},"references-count":84,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1111\/jan.16680"],"URL":"https:\/\/doi.org\/10.1111\/jan.16680","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JAN.16680\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.16680\/v2\/review1","asserted-by":"object"}]},"ISSN":["0309-2402","1365-2648"],"issn-type":[{"value":"0309-2402","type":"print"},{"value":"1365-2648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,15]]},"assertion":[{"value":"2024-03-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}