{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:12:36Z","timestamp":1790205156594,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:00:00Z","timestamp":1747353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:00:00Z","timestamp":1747353600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate factors affecting the quality of life of parents of children with spina bifida and examine how family resilience mediates between parental depression and quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross\u2013sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Secondary data analysis was performed using first\u2010year data from a five\u2010year spina bifida cohort project (2022\u20132026) in South Korea. The study included 162 parents of children aged 4\u201312\u2009years with spina bifida. Data were collected using the Korean version of the Family Resiliency Scale, the Center for Epidemiologic Studies Depression Scale, and the WHO Quality of Life Scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Factors were found to have a statistically significant influence on the quality of life of parents of children with spina bifida: the child's need for enemas, parental stress, parental depression, and family resilience. Baron &amp; Kenny's mediation analysis and bootstrap analysis in SPSS further confirmed that family resilience plays a mediating role between parental depression and quality of life. The indirect effect of parental depression on quality of life through family resilience was statistically significant, with a 95% confidence interval of [\u22120.2615, \u22120.0516].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The quality of life of parents with children with spina bifida is significantly influenced by both their child's daily symptom management and their psychological health. Family resilience plays a positive mediating role between parental depression and quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for the Profession and\/or Patient Care<\/jats:title>\n                    <jats:p>These findings support\u00a0a two\u2010track approach to family resilience building programs and the development of\u00a0core intervention strategies to enhance the quality of life in spina bifida families.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Reporting Method<\/jats:title>\n                    <jats:p>This study adhered to Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient Contribution<\/jats:title>\n                    <jats:p>There was no direct patient involvement in the study design, data collection, or analysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jan.17014","type":"journal-article","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T08:19:36Z","timestamp":1747383576000},"page":"1371-1381","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Factors Affecting the Quality of Life of Parents of Children With Spina Bifida: The Mediating Role of Family Resilience"],"prefix":"10.1111","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2971-2927","authenticated-orcid":false,"given":"Kyua","family":"Kim","sequence":"first","affiliation":[{"name":"College of Nursing and Brain Korea 21 FOUR Project Yonsei University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9272-8562","authenticated-orcid":false,"given":"Hyeseon","family":"Yun","sequence":"additional","affiliation":[{"name":"College of Nursing and Brain Korea 21 FOUR Project Yonsei University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7346-7902","authenticated-orcid":false,"given":"Hooyun","family":"Lee","sequence":"additional","affiliation":[{"name":"College of Nursing and Brain Korea 21 FOUR Project Yonsei University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2505-4112","authenticated-orcid":false,"given":"Kijun","family":"Song","sequence":"additional","affiliation":[{"name":"College of Nursing and Mo\u2010Im Kim Nursing Research Institute Yonsei University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5908-9033","authenticated-orcid":false,"given":"Marcia","family":"Van Riper","sequence":"additional","affiliation":[{"name":"School of Nursing University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4622-2437","authenticated-orcid":false,"given":"Eun Kyoung","family":"Choi","sequence":"additional","affiliation":[{"name":"College of Nursing and Mo\u2010Im Kim Nursing Research Institute Yonsei University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,16]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.51.6.1173"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jan.16589"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/sga.0000000000000135"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/rnj.0000000000000200"},{"issue":"1","key":"e_1_2_13_6_1","first-page":"59","article-title":"Integrated Adaptation of CES\u2010D in Korea","volume":"6","author":"Chon K. K.","year":"2001","journal-title":"Korean Journal of Health Psychology"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000002204"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPB.0000000000000063"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.7"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/dbp.0000000000000603"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.12934\/jkpmhn.2019.28.4.309"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2024.109817"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.3233\/prm\u2010200720"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22716"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2014.09.009"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1016351406336"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsu098"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedn.2023.11.020"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.3233\/prm\u2010160399"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/famp.12250"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2022.10.027"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare8040456"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0894318403251789"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2023.12.012"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e3181577511"},{"key":"e_1_2_13_27_1","volume-title":"Strengthening Family Resilience","author":"Walsh F.","year":"2015"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2023.1212014"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887\u2010024\u201005229\u20105"}],"container-title":["Journal of Advanced Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jan.17014","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jan.17014","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jan.17014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T15:26:06Z","timestamp":1769873166000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jan.17014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,16]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/jan.17014"],"URL":"https:\/\/doi.org\/10.1111\/jan.17014","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JAN.17014\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JAN.17014\/v1\/decision1","asserted-by":"object"}]},"ISSN":["0309-2402","1365-2648"],"issn-type":[{"value":"0309-2402","type":"print"},{"value":"1365-2648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,16]]},"assertion":[{"value":"2024-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}