{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:02:28Z","timestamp":1791219748160,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To systematically compare nurse\u2010led versus traditional rehabilitation in improving clinical outcomes for stroke survivors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review and meta\u2010analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were extracted from Cochrane, PubMed, Embase, and Web of Science (searched up to July 2024). Analyses with standardized mean differences (SMDs) and risk ratios (RRs) as the estimates were performed in Review Manager 5.4 and Stata 15.0. Randomized controlled trials investigating nurse\u2010led stroke rehabilitation with outcomes such as mental component summary (MCS) and physical component summary (PCS) of quality of life, self\u2010efficacy, National Institutes of Health Stroke Scale (NIHSS), stroke\u2010specific quality of life (SS\u2010QOL), Barthel Index (BI), Geriatric Depression Scale\u201015 (GDS\u201015), and pain were included. Sensitivity analyses and Grading of Recommendations Assessment, Development and Evaluation (GRADE) were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 12 articles were included. The quality assessment indicated that most studies did not have a serious risk of bias. Nurse\u2010led rehabilitation showed significant improvements in SS\u2010QOL (SMD: 3.33, 95% CI: 1.26, 5.40; very low\u2010quality evidence), depressive symptoms (GDS\u201015, SMD: \u22122.21; 95% CI: \u22122.80, \u22121.63; high\u2010quality evidence), pain (SMD: \u22121.61; 95% CI: \u22122.14, \u22121.08; high\u2010quality evidence), and BI (SMD: 0.24, 95% CI: 0.01, 0.48; low\u2010quality evidence). However, there were no significant differences in MCS, PCS, self\u2010efficacy, or NIHSS between the two groups. Sensitivity analysis showed that the results for SS\u2010QOL and BI were unstable and should be interpreted with caution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nurse\u2010led rehabilitation is effective in improving psychological outcomes, particularly depression (GDS\u201015) and pain, although this high\u2010quality evidence is based on a single study. Functional independence (BI) and SS\u2010QOL are also improved, but the evidence for these outcomes is of low quality and highly unstable in sensitivity analyses. No significant benefits are found for other outcomes. The evidence quality varies, and future high\u2010quality studies are needed to confirm these findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for the Profession and\/or Patient Care<\/jats:title>\n                    <jats:p>Incorporating nurse\u2010led rehabilitation into stroke guidelines and implementing standardized depression screening programs and non\u2010pharmacological pain interventions in community rehabilitation could be beneficial for populations with depressive symptoms and chronic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Reporting Method<\/jats:title>\n                    <jats:p>This study adhered to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses) guidelines for transparent reporting of systematic reviews.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>This study did not include patient or public involvement in its design, conduct, or reporting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jan.70337","type":"journal-article","created":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:10:13Z","timestamp":1761959413000},"page":"6970-6981","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating the Clinical Effectiveness of Nurse\u2010Led Rehabilitation for Stroke Survivors: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"82","author":[{"given":"Min","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Neurology The First Hospital of Hunan University of Chinese Medicine  Changsha Hunan 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