{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:49:38Z","timestamp":1791427778845,"version":"4.3.3"},"reference-count":72,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Nursing"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate the effectiveness, including economic outcomes, of specialist cancer nurse\u2010led interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A systematic umbrella review, reported in accordance with PRISMA guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Systematically conducted reviews reporting any effectiveness or cost\u2010effectiveness outcomes published between January 2014 and June 2025 were included. Each review was screened and a quality assessment conducted by two authors. Results were narratively synthesised with specialist cancer nurse\u2010led interventions categorised according to the Omaha System Intervention Scheme.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>CINAHL, Cochrane DSR, Medline, PsycINFO, PROSPERO and Google Scholar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>34 of 1389 reviews screened were included, reporting on 330 individual primary studies. Over 190,000 people with various types of cancer were represented. Cancer nurse\u2010led interventions described in the reviews were delivered face\u2010to\u2010face, via telephone or internet and included (1) teaching, guiding and counselling; (2) treatments and procedures; (3) case management; and (4) surveillance interventions. Cancer nurse\u2010led interventions were more effective compared to alternative care models at improving self\u2010management and behaviour capabilities in 10\/14 reviews (71%), symptom burden in 17\/29 (58%) and patient satisfaction in 10\/17 (59%). Nurse\u2010led interventions demonstrated comparable effects on quality of life, survival, economic outcomes overall when compared to alternative care models. Limited full or partial economic evaluations were found. Usual care was not well described in the reviews, but in primary studies, over 80% of interventions were delivered as an addition to usual care rather than as an alternative to other healthcare professionals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Nurses are effective at delivering care across the cancer trajectory but are most effective at self\u2010management and behavioural support and symptom management. Robust full economic evaluations are needed to determine the value of cancer nurse\u2010led interventions. Findings from this review can be used to guide policy and strategic planning on where specialist cancer nurses are best placed for maximum impact. No Patient or Public Contribution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Protocol Registration<\/jats:title>\n                    <jats:p>A protocol was registered with PROSPERO (CRD42024559328), which included the methods for this umbrella review.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jan.70768","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:51:37Z","timestamp":1791424297000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Doing It All or Doing It Best: An Umbrella Review of the Effectiveness of Specialist Cancer Nurse\u2010Led Care"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0250-1848","authenticated-orcid":false,"given":"Carla","family":"Thamm","sequence":"first","affiliation":[{"name":"Flinders LiveWell Cancer Research Centre, Caring Futures Institute, College of Health and Enablement Flinders University  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4859-0421","authenticated-orcid":false,"given":"Elise","family":"Button","sequence":"additional","affiliation":[{"name":"Flinders LiveWell Cancer Research Centre, Caring Futures Institute, College of Health and Enablement Flinders University  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1273-5368","authenticated-orcid":false,"given":"Megan","family":"Crichton","sequence":"additional","affiliation":[{"name":"Cancer and Palliative Care Outcomes Centre, School of Nursing Queensland University of Technology  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4050-031X","authenticated-orcid":false,"given":"Andreas","family":"Charalambous","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Nursing Department Cyprus University of Technology  Limassol Cyprus"},{"name":"Faculty of Health Sciences, Nursing Department University of Turku  Turku Finland"},{"name":"Director e\u2010OncoRise, Research Centre for Oncology and Palliative Care Cyprus University of Technology  Limassol Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Christina","sequence":"additional","affiliation":[{"name":"Flinders LiveWell Cancer Research Centre, Caring Futures Institute, College of Health and Enablement Flinders University  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6326-8707","authenticated-orcid":false,"given":"Murray R.","family":"Turner","sequence":"additional","affiliation":[{"name":"Faculty of Health University of Canberra  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