{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:24:44Z","timestamp":1790317484971,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T00:00:00Z","timestamp":1607817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["U01AG051412"],"award-info":[{"award-number":["U01AG051412"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Research Intellect Disabil"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The accuracy of the National Task Group\u2010Early Detection Screen for Dementia (NTG\u2010EDSD) was evaluated in a sample of 185 adults with Down syndrome (DS), emphasizing \u2018mild cognitive impairment (MCI\u2010DS)\u2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Knowledgeable informants were interviewed with the NTG\u2010EDSD, and findings were compared to an independent dementia status rating based on consensus review of detailed assessments of cognition, functional abilities and health status (including physician examination).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Results indicated that sections of the NTG\u2010EDSD were sensitive to MCI\u2010DS, with one or more concerns within the \u2018Memory\u2019 or \u2018Language and Communication\u2019 domains being most informative.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The NTG\u2010EDSD is a useful tool for evaluating dementia status, including MCI\u2010DS. However, estimates of sensitivity and specificity, even for detecting frank dementia, indicated that NTG\u2010EDSD findings need to be supplemented by additional sources of relevant information to achieve an acceptable level of diagnostic\/screening accuracy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jar.12849","type":"journal-article","created":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T02:27:49Z","timestamp":1607912869000},"page":"905-915","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Evaluation of the National Task Group\u2010Early Detection Screen for Dementia: Sensitivity to \u2018mild cognitive impairment\u2019 in adults with Down syndrome"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7842-8600","authenticated-orcid":false,"given":"Wayne","family":"Silverman","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of California, Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon J.","family":"Krinsky\u2010McHale","sequence":"additional","affiliation":[{"name":"New York State Institute for Basic Research in Developmental Disabilities Staten Island NY USA"},{"name":"Department of Psychiatry University of California, Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Neurology Massachusetts General Hospital Harvard University Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Diana Rosas","sequence":"additional","affiliation":[{"name":"Department of Neurology Massachusetts General Hospital Harvard University Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christy","family":"Hom","sequence":"additional","affiliation":[{"name":"New York State Institute for Basic Research in Developmental Disabilities Staten Island NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Doran","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of California, Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Pulsifer","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital Harvard University Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Lott","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of California, Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Schupf","sequence":"additional","affiliation":[{"name":"Sergievsky Center Taub Institute New York CA USA"},{"name":"Department of Neurology College of Physicians and Surgeons Columbia University New York CA USA"},{"name":"Department of Epidemiology School of Public Health Columbia University New York CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The Alzheimer\u2019s Disease in Down Syndrome (ADDS) Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1992.tb02009.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.008"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.1997.tb00692.x"},{"key":"e_1_2_6_5_1","volume-title":"Developmental Test of Visual\u2010Motor Integration","author":"Beery K. 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