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Two linear mixed models and a model including the variables that best predicted group membership were built.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Behavioural Regulation Index (BRI) (Behaviour Rating Inventory of Executive Function test) and the model composed of BRI, abstraction and delayed verbal memory were the variable and model best predicting group membership, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Suggest a diagnosis of MCI when BRI is the earliest change perceived by caregivers and this is combined with low scores in abstract thinking, and when an amnesic pattern in delayed verbal memory is observed, but adaptive skills are preserved.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jar.12959","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T07:13:25Z","timestamp":1635146005000},"page":"495-505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Proposed diagnostic criteria for mild cognitive impairment in Down syndrome population"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0414-0599","authenticated-orcid":false,"given":"Susanna","family":"Esteba\u2010Castillo","sequence":"first","affiliation":[{"name":"Specialized Service in Mental Health and Intellectual Disability Institute of Health Assistance  Girona Spain"},{"name":"Neurodevelopmental Group [Girona Biomedical Research Institute]\u2013IDIBGI Institute of Health Assistance (IAS)  Girona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3342-6572","authenticated-orcid":false,"given":"Javier","family":"Garcia\u2010Alba","sequence":"additional","affiliation":[{"name":"Research and Psychology in Education Department (Faculty of Education) Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emili","family":"Rodr\u00edguez\u2010Hildago","sequence":"additional","affiliation":[{"name":"Specialized Service in Mental Health and Intellectual Disability Institute of Health Assistance  Girona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0361-0771","authenticated-orcid":false,"given":"Luc\u00eda","family":"Vaquero","sequence":"additional","affiliation":[{"name":"Laboratory of Cognitive and Computational Neuroscience, Department of Legal Medicine, Psychiatry and Pathology (Faculty of Medicine) Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Novell","sequence":"additional","affiliation":[{"name":"Specialized Service in Mental Health and Intellectual Disability Institute of Health Assistance  Girona Spain"},{"name":"Neurodevelopmental Group [Girona Biomedical Research Institute]\u2013IDIBGI Institute of Health Assistance (IAS)  Girona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6259-8226","authenticated-orcid":false,"given":"Fernando","family":"Moldenhauer","sequence":"additional","affiliation":[{"name":"Adults' Section of the Down syndrome Department, Internal Medicine Department La Princesa University Hospital  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4222-2309","authenticated-orcid":false,"given":"Miguel \u00c1ngel","family":"Castellanos","sequence":"additional","affiliation":[{"name":"Department of Methodology for Behavioral Science Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.008"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.107.s179.7.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.2000.7359"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/s1355617706061078"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/s1355617701755063"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.1545"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(16)00063-6"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2017.10.341"},{"key":"e_1_2_10_12_1","unstructured":"RCore Team(2020).R: A language and environment for statistical computing. 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