{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T14:49:24Z","timestamp":1776091764485,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Research Intellect Disabil"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Most adults with Down syndrome develop Alzheimer's disease (AD) pathology in their 30s, yet research into cognitive health programmes for this group remains limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A mixed\u2010methods feasibility randomised control trial (RCT) evaluated an adapted, manualised group\u2010based cognitive stimulation therapy (CST) programme for adults with Down syndrome (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200912;\n                      <jats:italic>M<\/jats:italic>\n                      <jats:sub>age<\/jats:sub>\n                      \u2009=\u200930) without dementia. Participants were randomly assigned to CST (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096) or control (services as usual;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096), with assessments at baseline, post\u2010programme, and four\u2010month follow\u2010up by a blinded researcher.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The adapted CST was feasible, with high attendance, strong satisfaction, and good CST programme fidelity (all &gt;\u200985%). CST participants showed significant gains in adaptive behaviour at post\u2010programme, maintained at follow\u2010up, and a trend towards improved episodic memory at post\u2010programme.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Manualised group\u2010based CST can be successfully adapted for younger adults with Down syndrome and shows promise in supporting cognitive health for this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jar.70120","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T08:47:06Z","timestamp":1757494026000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Proactive Cognitive Stimulation for Younger Adults With Down Syndrome. 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