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High rates of aggression are reported in SAS, yet the profile and contributing factors remain poorly understood. This study explored caregiver perspectives on aggression in SAS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Caregivers of 37 individuals with SAS (\n                      <jats:italic>M<\/jats:italic>\n                      age\u2009=\u200911.42\u2009years) completed questionnaires on adaptive ability, aggression and behavioural function. Semi\u2010structured interviews with 34 caregivers explored contextual factors such as triggers, co\u2010occurring emotions, and management strategies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Aggression was reported in 87% of individuals, with frequent forms including pulling\/grabbing (84%) and hitting with a body part (69%) or object (53%). Aggression was often linked to frustration, anxiety, and triggers relating to demands, routines, repetitive behaviour, and tangibles. Caregivers described varied management strategies and background factors influencing aggression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Findings provide the first detailed description of aggression in SAS, highlighting vulnerabilities to guide tailored behavioural assessment and interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jar.70247","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T12:46:42Z","timestamp":1779454002000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Understanding Aggression in\n                    <scp>SATB2<\/scp>\n                    \u2010Associated Syndrome: A Mixed\u2010Methods Study Exploring Caregiver Perspectives"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1036-3177","authenticated-orcid":false,"given":"Lauren","family":"Shelley","sequence":"first","affiliation":[{"name":"School of Psychology, College of Health and Life Sciences Aston University  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4328-1653","authenticated-orcid":false,"given":"Effie","family":"Pearson","sequence":"additional","affiliation":[{"name":"School of Psychology, College of Health and Life Sciences Aston University  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0555-6043","authenticated-orcid":false,"given":"Joanne","family":"Tarver","sequence":"additional","affiliation":[{"name":"School of Psychology, College of Health and Life Sciences Aston University  Birmingham 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