{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:38:23Z","timestamp":1792737503425,"version":"4.5.0"},"reference-count":58,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Research Intellect Disabil"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We aimed to evaluate the effectiveness of resistance training (RT) in people with Down syndrome (DS) as a way of improving strength, physical and metabolic function, and possible adverse effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Systematic review and meta\u2010analysis of RCTs in PubMed, PEDro, Scopus, and WoS databases in September\u20102023, registered in PROSPERO (CRD42022312810). Methodological quality and risk of bias were analysed using the PEDro scale, the Downs &amp; Black Checklist, and the Cochrane Collaboration Risk of Bias Tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixteen articles were included. RT increased the strength (SMD\u2009=\u20091.88; 95% CI\u2009=\u2009(1.26; 2.51);\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200972%) and improved physical function (SMD\u2009=\u2009\u22120.58; 95% CI\u2009=\u2009(\u22121.06; \u22120.11);\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200913%), but there were no clear results on whether it improved anthropometric and cardiorespiratory measures. There were no serious adverse effects.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>An increase in overall and maximal muscle strength and improved physical function was produced by RT in DS people. RT is a safe technique as serious adverse effects were not produced.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jar.70302","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:29:14Z","timestamp":1788874154000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Resistance Training in People With Down Syndrome: Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6114-6981","authenticated-orcid":false,"given":"Mar\u00eda Jes\u00fas","family":"Benzo Iglesias","sequence":"first","affiliation":[{"name":"Health Research Centre, Humanidades\u2010498 Research Group, Department of Nursing, Physiotherapy and Medicine University of Almer\u00eda  Almer\u00eda Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda","family":"Torres \u00c1lamo","sequence":"additional","affiliation":[{"name":"La Vega Clinic  Almer\u00eda Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9567-462X","authenticated-orcid":false,"given":"Alejandro","family":"Salazar","sequence":"additional","affiliation":[{"name":"Department of Statistics and Operational Research University of Cadiz  Cadiz Spain"},{"name":"Institute of Research and Innovation in Biomedical Sciences of the Province of Cadiz (INiBICA) University of Cadiz  Cadiz Spain"},{"name":"Observatory of Pain, Gr\u00fcnenthal Foundation University of Cadiz  Cadiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0662-2487","authenticated-orcid":false,"given":"Patricia","family":"Rocamora P\u00e9rez","sequence":"additional","affiliation":[{"name":"Health Research Centre, Humanidades\u2010498 Research Group, Department of Nursing, Physiotherapy and Medicine University of 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