{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T20:18:03Z","timestamp":1789589883410,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,11,6]],"date-time":"2012-11-06T00:00:00Z","timestamp":1352160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:p><jats:bold>Anatomical Predictors for Acute and Mid\u2010Term Success of Cryoballoon Ablation.<\/jats:bold>\u2002<jats:bold><jats:italic>Introduction:<\/jats:italic><\/jats:bold> Cryoballoon (CB) pulmonary vein isolation (CB\u2010PVI) for the treatment of paroxysmal atrial fibrillation (AF) has been demonstrated to be safe and reliable. Preprocedural patient selection to address the high variability in pulmonary vein (PV) anatomy may improve the acute and chronic success of CB\u2010PVI. The purpose of this study was to identify anatomical predictors for CB\u2010PVI failure using the 28 mm balloon.<\/jats:p><jats:p><jats:bold>\n            <jats:italic>Methods and Results<\/jats:italic>\n          <\/jats:bold>: We included 47 patients with paroxysmal AF undergoing CB\u2010PVI with the 28 mm CB. Anatomical global left atrial and PV selective parameters were quantified from 3\u2010dimensional reconstructed preprocedural computed tomography or magnetic resonance imaging data. The mean follow\u2010up was 26 \u00b1 9 months (range: 12\u201332 months). Multivariate logistic regression analysis revealed that a continuous sharp left lateral ridge between the left PVs and the left lateral appendage (OR, 7.09; 95% CI, 1.17\u201343.47) and a sharp carina between the left superior and left inferior PV (OR, 5.99; 95% CI, 1.33\u201327.03) predict acute and mid\u2010term failure. For the right inferior PVs, a non\u2010perpendicular angle between the axis of the PV and the ostial plane (OR, 6.33; 95% CI, 1.20\u201333.33) and an early branching PV with change in the axis angle (OR, 7.41; 95% CI, 1.44\u201338.46) were predictors of acute and mid\u2010term failure.<\/jats:p><jats:p><jats:bold>\n            <jats:italic>Conclusion:<\/jats:italic>\n          <\/jats:bold> Anatomical variables preventing maximal heat transfer from the tissue to the CB could be identified as predictors for CB\u2010PVI failure with the 28 mm balloon. These findings may be a step toward a more tailored ablation strategy based on individual anatomical variations. <jats:italic>(J Cardiovasc Electrophysiol, Vol. 24, pp. 132\u2010138, February 2013)<\/jats:italic><\/jats:p>","DOI":"10.1111\/jce.12003","type":"journal-article","created":{"date-parts":[[2012,8,29]],"date-time":"2012-08-29T11:57:08Z","timestamp":1346241428000},"page":"132-138","source":"Crossref","is-referenced-by-count":70,"title":["Anatomical Predictors for Acute and Mid\u2010Term Success of Cryoballoon Ablation of Atrial Fibrillation Using the 28 mm Balloon"],"prefix":"10.1111","volume":"24","author":[{"given":"SVEN","family":"KNECHT","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MICHAEL","family":"K\u00dcHNE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DAVID","family":"ALTMANN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PETER","family":"AMMANN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BEAT","family":"SCHAER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STEFAN","family":"OSSWALD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHRISTIAN","family":"STICHERLING","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,11,6]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus027"},{"key":"e_1_2_7_3_2","first-page":"588","article-title":"Characterization of the pulmonary vein tissue temperature response to cryo therapy: Threshold of irreversible cryothermal injury","volume":"116","author":"Kolasa MW","year":"2007","journal-title":"Circulation"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.04.021"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2303030315"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn570"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.06.017"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus041"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.07.029"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000061951.81767.4E"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm606"},{"key":"e_1_2_7_12_2","first-page":"214","article-title":"Cryoballoon ablation for pulmonary vein isolation in patients with paroxysmal atrial fibrillation","volume":"140","author":"K\u00fchne M","year":"2010","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.08.028"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-77244-8_17"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm227"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun352"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.10.038"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01703.x"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur356"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2006.00548.x"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.192419"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euq388"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2011.02148.x"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.690578"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup331"},{"key":"e_1_2_7_26_2","unstructured":"SchmidtM DorwarthU StraubeF DaccarettM RieberJ WankerlM KriegJ LeberAW EbersbergerU HuberA RummenyE HoffmannE:Cryoballoon in AF ablation: Impact of PV ovality on AF recurrence.Int J Cardiol. 2011 Dec 27. 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