{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:17:11Z","timestamp":1790921831575,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T00:00:00Z","timestamp":1361750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Left Ventricular Tachycardia in Pediatrics<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate the clinical presentation and outcomes of pediatric patients with ventricular tachycardia (VT) originating from left heart structures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>This international multicenter retrospective study including 152 patients (age 10.0 \u00b1 5.1 years, 62% male), divided into those with fascicular VT (85%, 129\/152) and nonfascicular LV VT (15%, 23\/152). All patients had a normal heart structure or only a minor cardiac abnormality. Adenosine was largely ineffective in both groups (tachycardia termination in 4\/74 of fascicular VT and 0\/5 of nonfascicular LV VT). In fascicular VT, calcium channel blockers were effective in 80% (74\/92); however, when administered orally, there was a 21% (13\/62) recurrence rate. In nonfascicular LV VT, a variety of antiarrhythmic therapies were used with no one predominating. Ablation procedures were successful in 71% (72\/102) of fascicular VT and 67% (12\/18) of nonfascicular LV VT on an intention to treat analysis. Major complications occurred in 5 patients with fascicular VT and 1 patient with nonfascicular LV VT. After a follow\u2010up period of 2 years (1 day to 15 years), 72% of all patients with fascicular VT were off medications with no tachycardia recurrence. One patient died of noncardiac causes. In nonfascicular LV VT, follow\u2010up was 3.5 years (0.5\u201315 years), P = 0.38. A total of 65% of these patients were free from arrhythmias. Two patients died suddenly (P &lt; 0.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The clinical course and outcomes of pediatric patients with fascicular VT and nonfascicular LV VT are varied. Catheter ablation procedures can be curative.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.12105","type":"journal-article","created":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T12:19:48Z","timestamp":1359116388000},"page":"640-648","source":"Crossref","is-referenced-by-count":72,"title":["Fascicular and Nonfascicular Left Ventricular Tachycardias in the Young: An International Multicenter Study"],"prefix":"10.1111","volume":"24","author":[{"given":"KATHRYN K.","family":"COLLINS","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics The Children's Hospital, University of Colorado  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MICHAEL S.","family":"SCHAFFER","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics The Children's Hospital, University of Colorado  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LEONARDO","family":"LIBERMAN","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Children's Hospital of NY\u2010Presbyterian  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELIZABETH","family":"SAAREL","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Primary Children's Hospital  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MARIA","family":"KNECHT","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics The Children's Memorial Health Insitute  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RONN E.","family":"TANEL","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DAVID","family":"BRADLEY","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics C. 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Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANNE M.","family":"DUBIN","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Stanford University  Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THOMAS","family":"PAUL","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Georg\u2010August\u2010University  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JACK","family":"SALERNO","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Children's Heart Center  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YANIV","family":"BAR\u2010COHEN","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Children's Hospital  Los Angeles California 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New York  New Hyde Park New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANJAN","family":"BATRA","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Childrens Hospital of Orange County University of California\u2010Irvine  Orange California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOSE M.","family":"MOLTEDO","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Clinica y Maternidad Suizo Argentina  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GEORGE F.","family":"VAN HARE","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Washington University School of Medicine\/St. Louis Children's Hospital  St. Louis Missouri 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