{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T03:18:33Z","timestamp":1768274313396,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T00:00:00Z","timestamp":1365465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Hyperthyroidism and AF Ablation<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Many patients with atrial fibrillation (AF) receive amiodarone. Amiodarone\u2010induced hyperthyroidism (AIH) may develop as a complication. We hypothesized that pulmonary vein (PV) isolation in patients with paroxysmal AF and history of AIH may yield a lower success rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Among 704 patients who underwent AF ablation in our center between 2007 and 2010, we identified 20 patients (mean age 58.3 \u00b1 5.0 years; 11 males) with paroxysmal AF and overt AIH in the past. The control group consisted of 40 patients with amiodarone\u2010refractory AF and no thyroid dysfunction. All patients underwent circumferential PV isolation. During redo procedures all tachycardias were targeted for ablation. During a 12\u2010month follow\u2010up, in the AIH group 6 (30%) patients were arrhythmia free after a single procedure, in comparison to 25 (62.5%) controls (P = 0.01). Atrial tachycardia (AT) was registered in 7 (35%) AIH patients and in 1 (2.5%) control patient (P = 0.001). AF recurred in 10 (50%) AIH versus 15 (37.5%) control patients (P = 0.2). Redo ablation was performed in 7 (35%) AIH patients and in 3 (7.5%) non\u2010AIH patients (P = 0.01). During a redo procedure a PV\u2010unrelated tachycardia was diagnosed in 5 (25%) AIH patients (vs 0 in the controls, P = 0.003). After the last performed ablation, 12 (60%) AIH patients and 28 (70%) controls had no recurrence, P = 0.56. AIH was an independent predictor of ATs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PV isolation alone has a lower efficacy for preventing recurrence in paroxysmal AF in AIH patients. After repeat ablations, overall freedom from tachyarrhythmias is similar to patients with no history of thyroid dysfunction.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12140","type":"journal-article","created":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T20:23:49Z","timestamp":1363206229000},"page":"888-893","source":"Crossref","is-referenced-by-count":13,"title":["Catheter Ablation of Paroxysmal Atrial Fibrillation in Patients with Previous Amiodarone\u2010Induced Hyperthyroidism: A Case\u2013Control Study"],"prefix":"10.1111","volume":"24","author":[{"given":"EVGENY N.","family":"MIKHAYLOV","sequence":"first","affiliation":[{"name":"Department of Electrophysiology Almazov Federal Heart, Blood and Endocrinology Centre  Saint\u2010Petersburg Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VIKTORYA S.","family":"ORSHANSKAYA","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Almazov Federal Heart, Blood and Endocrinology Centre  Saint\u2010Petersburg Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALEXANDER D.","family":"LEBEDEV","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Almazov Federal Heart, Blood and Endocrinology Centre  Saint\u2010Petersburg Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TAMAS","family":"SZILI\u2010TOROK","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Thoraxcenter, Erasmus MC  Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DMITRY S.","family":"LEBEDEV","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Almazov Federal Heart, Blood and Endocrinology Centre  Saint\u2010Petersburg Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.859116"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.07.038"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2007.10.022"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2008.02250.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"e257","DOI":"10.1161\/CIRCULATIONAHA.106.177292","article-title":"ACC\/AHA\/ESC 2006 Guidelines for the Management of Patients with Atrial Fibrillation","volume":"114","author":"Fuster V","year":"2006","journal-title":"Circulation"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2001.119370"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000169643"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01731-4"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.01071.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.06.016"},{"key":"e_1_2_7_12_1","first-page":"IV617","article-title":"Female gender is associated with the presence of non\u2010pulmonary vein triggers of atrial fibrillation","volume":"108","author":"Sauer WH","year":"2003","journal-title":"Circulation"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.928903"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.04052.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-007-9088-y"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-09-0708"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.12140","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.12140","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.12140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T01:05:10Z","timestamp":1696208710000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.12140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,9]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/jce.12140"],"URL":"https:\/\/doi.org\/10.1111\/jce.12140","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,9]]}}}