{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:35:09Z","timestamp":1791045309806,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,7,11]],"date-time":"2013-07-11T00:00:00Z","timestamp":1373500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>frQRS and Outcomes in ARVC\/D<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fragmented QRS (frQRS) complex, with various morphology, has been recently described as a diagnostic criterion of arrhythmogenic right ventricular cardiomyopathy\/dysplasia (ARVC\/D). However, there are little data regarding the prognostic role of frQRS in these patients. Therefore, we aimed to investigate the association of frQRS with arrhythmic events in patients with ARVC\/D.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy\u2010eight patients (51 men, 65.4%; mean age: 31.25 \u00b1 11.5 years) with the diagnosis of ARVC\/D according to 2010 modified Task Force Criteria were analyzed retrospectively. Baseline ECG evaluation revealed frQRS complex in 46 patients (59%). Eleven patients with complete\/incomplete right bundle branch block were excluded from the study. The phenomenon of frQRS was defined as deflections at the beginning of the QRS complex, on top of the R\u2010wave, or in the nadir of the S\u2010wave similar to the definition in CAD in either one right precordial lead or in more than one lead including all standard ECG leads.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During 38 \u00b1 14 months follow\u2010up period, 3 patients (3.8%) died suddenly, 36 patients (46.1%) experienced arrhythmic events (32 ventricular tachycardias [VTs] and 4 ventricular fibrillation [VF], 30 in the ICD group). The frQRS was significantly associated with arrhythmic events (P &lt; 0.001). Also, the number of ECG leads with frQRS complex was higher in patients with arrhythmic events (5.08 \u00b1 2.5 vs 1.14 \u00b1 1.7, P &lt; 0.001, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The frQRS complex on standard 12\u2010lead ECG predicts fatal and nonfatal arrhythmic events in patients with ARVC\/D. Therefore, large scale and prospective studies are needed to confirm those findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12202","type":"journal-article","created":{"date-parts":[[2013,6,10]],"date-time":"2013-06-10T17:24:58Z","timestamp":1370885098000},"page":"1260-1266","source":"Crossref","is-referenced-by-count":64,"title":["Fragmented QRS Complex Predicts the Arrhythmic Events in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy\/Dysplasia"],"prefix":"10.1111","volume":"24","author":[{"given":"U\u011eUR","family":"CANPOLAT","sequence":"first","affiliation":[{"name":"T\u00fcrkiye Y\u00fcksek \u0130htisas Training and Research Hospital Cardiology Clinic  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GIRAY","family":"KABAK\u00c7I","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KUDRET","family":"AYTEMIR","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MUHAMMET","family":"DURAL","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LEVENT","family":"\u015eAHINER","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HIKMET","family":"YORGUN","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HAMZA","family":"SUNMAN","sequence":"additional","affiliation":[{"name":"Di\u015fkapi Yildirim Beyazit Research and Educational Hospital Cardiology Clinic  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ERG\u00dcN","family":"BARI\u015e KAYA","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LALE","family":"TOKG\u00d6ZO\u011eLU","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ALI","family":"OTO","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60256-7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2012.02412.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.660241"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2004.01.001"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.595892"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.107.763284"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.09.065"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2011.00442.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.06.024"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.09.008"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.770917"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.07.012"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.10.019"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq025"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.913871"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr040"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1542-474X.2003.08212.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2011.02288.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.963066"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000121738.88273.43"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.21.2334"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.72.3.596"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(92)90648-F"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0b013e32834bed0a"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000103130.33451.D2"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000143375.93288.82"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2008.01.002"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0b013e328333d35d"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.12202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.12202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.12202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:43:41Z","timestamp":1696261421000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.12202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,11]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/jce.12202"],"URL":"https:\/\/doi.org\/10.1111\/jce.12202","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,11]]}}}