{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:43:32Z","timestamp":1792165412309,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T00:00:00Z","timestamp":1401926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001674","name":"Fondation Leducq","doi-asserted-by":"crossref","award":["09 CVD 03"],"award-info":[{"award-number":["09 CVD 03"]}],"id":[{"id":"10.13039\/501100001674","id-type":"DOI","asserted-by":"crossref"}]},{"name":"European Union Seventh Framework Program","award":["FP7\/2007-2013"],"award-info":[{"award-number":["FP7\/2007-2013"]}]},{"name":"Agreement HEALTH","award":["F2-2010-261057"],"award-info":[{"award-number":["F2-2010-261057"]}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"crossref","award":["ANR-10-IAHU-04"],"award-info":[{"award-number":["ANR-10-IAHU-04"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Atrial Function After Persistent AF Ablation<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The atrial outcome after extensive ablation is unknown. We sought to quantify atrial structure and function years after successful ablation for persistent atrial fibrillation (PsAF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>We studied after 80 \u00b1 15 months 26 patients (54 \u00b1 8 years, 1 woman) with PsAF successfully treated by ablation (2.2 \u00b1 0.7 stepwise approach procedures, cumulative RF duration 126 \u00b1 37 minutes). At follow\u2010up atrial scar burden and atrial outflows were quantified using delayed\u2013enhanced and velocity\u2010encoded MRI, respectively. Cine imaging was used to quantify atrial conduit function (CF), active emptying fraction (AEF), expansion index (EI), and the inter\u2010appendage mechanical activation delay. Patients underwent exercise testing at baseline and follow\u2010up. LA and RA scar extent were 29 \u00b1 6 and 4.3 \u00b1 2.8%, respectively. LA and RA AEF were 10.0 \u00b1 5.3 and 30 \u00b1 8%. Mean inter\u2010appendage delay was 83 \u00b1 47 ms [42\u2013217]. Complete LAA isolation was found in 3 patients. A wave was absent in 9\/26 patients. LA scar extent related to the number of procedures (R = 0.58, P = 0.002) and total RF duration (R = 0.56, P = 0.003). Among follow\u2010up characteristics, LA scar extent related to LAAEF (R = \u22120.73, P &lt; 0.0001), LAEI (R = \u22120.64, P = 0.0003), A\u2010wave peak (R = \u22120.72, P &lt; 0.0001), and inter\u2010appendage mechanical delay (R = 0.47, P = 0.02). At multivariable analysis, LA scar extent was independently related to LAAEF and LAEI. LAAEF and LA scar extent correlated with exercise capacity at follow\u2010up (R = 0.44, P = 0.02, and R = \u22120.40; P = 0.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LA contractility and compliance are markedly impaired years after successful PsAF ablation. LA dysfunction is closely related to scar burden.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12449","type":"journal-article","created":{"date-parts":[[2014,5,2]],"date-time":"2014-05-02T17:12:39Z","timestamp":1399050759000},"page":"671-679","source":"Crossref","is-referenced-by-count":63,"title":["Atrial Structure and Function 5 Years After Successful Ablation for Persistent Atrial Fibrillation: An MRI Study"],"prefix":"10.1111","volume":"25","author":[{"given":"HUBERT","family":"COCHET","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Imaging CHU \/ Universit\u00e9 de Bordeaux  Pessac France"},{"name":"L'Institut de Rythmologie et de Mod\u00e9lisation Cardiaque LIRYC CHU \/ Universit\u00e9 de Bordeaux \/ INSERM U1045  Pessac France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DANIEL","family":"SCHERR","sequence":"additional","affiliation":[{"name":"Department of cardiac pacing and electrophysiology CHU \/ Universit\u00e9 de Bordeaux  Pessac 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