{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:01:15Z","timestamp":1771920075095,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,7,4]],"date-time":"2014-07-04T00:00:00Z","timestamp":1404432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Gender and Atrial Electrophysiology<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Gender\u2010based differences in the clinical nature of cardiac arrhythmias such as atrial fibrillation (AF) are well established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to identify any such gender\u2010based differences in the underlying pulmonary vein and atrial substrate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Thirty\u2010eight patients with no history of AF undergoing catheter ablation for supraventricular tachycardia (SVT) and 55 with paroxysmal or persistent AF undergoing catheter ablation of AF underwent detailed electroanatomic mapping of the pulmonary veins and atria. Refractory periods in multiple locations, sinus node function, endocardial bipolar voltage, pulmonary vein and atrial conduction, and bipolar electrogram complexity were analyzed. There were no significant between\u2010gender differences in age or other clinical variables known to impact on the atrial or pulmonary vein substrate. In neither the AF nor the non\u2010AF cohorts were there any significant differences in atrial or pulmonary vein refractoriness, sinus node function, any measure of PV electrophysiology, or any measure of atrial electrophysiology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No systematic between\u2010gender differences were observed in the PV or atrial substrate either in those with or without a history of AF, with a similar prevalence of the cardiovascular comorbidities frequently associated with atrial remodeling and AF seen in both male and female groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12465","type":"journal-article","created":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T12:18:48Z","timestamp":1401970728000},"page":"1065-1070","source":"Crossref","is-referenced-by-count":19,"title":["Absence of Gender\u2010Based Differences in the Atrial and Pulmonary Vein Substrate: A Detailed Electroanatomic Mapping Study"],"prefix":"10.1111","volume":"25","author":[{"given":"TOMOS E.","family":"WALTERS","sequence":"first","affiliation":[{"name":"Department of Cardiology The Royal Melbourne Hospital  Melbourne Australia"},{"name":"The Department of Medicine The University of Melbourne  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANDREW W.","family":"TEH","sequence":"additional","affiliation":[{"name":"The Department of Cardiology The Austin Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"STEVEN","family":"SPENCE","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Royal Melbourne Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOSEPH B.","family":"MORTON","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Royal Melbourne Hospital  Melbourne Australia"},{"name":"The Department of Medicine The University of Melbourne  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PETER M.","family":"KISTLER","sequence":"additional","affiliation":[{"name":"The Department of Medicine The University of Melbourne  Melbourne Australia"},{"name":"The Department of Cardiology The Alfred Hospital and Baker IDI  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JONATHAN M.","family":"KALMAN","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Royal Melbourne Hospital  Melbourne Australia"},{"name":"The Department of Medicine The University of Melbourne  Melbourne 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