{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:58:26Z","timestamp":1791219506374,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,7,7]],"date-time":"2014-07-07T00:00:00Z","timestamp":1404691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Ablation Outcome in Silent Longstanding Persistent AF<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Impact of catheter ablation on exercise performance, quality of life (QoL) and symptom perception in asymptomatic longstanding persistent AF (LSP\u2010AF) patients has not been reported yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Sixty\u2010one consecutive patients (mean age 62 \u00b113 years, 71% males) with asymptomatic LSP\u2010AF undergoing first catheter ablation were enrolled. Extended pulmonary vein antrum isolation plus ablation of complex fractionated atrial electrograms and nonpulmonary vein triggers was performed in all. QoL survey was taken at baseline and 12\u2010months postablation, using Short Form\u201036 (SF\u201036). Information on arrhythmia perception was obtained using a standard questionnaire and corroborating symptoms with documented evidence of arrhythmia. Exercise tests were performed on 38 patients at baseline and 5 months after procedure. Recurrence was assessed using event recorder, cardiology evaluation, electrocardiogram, and 7\u2010day holter monitoring. After 20 \u00b1 5 months follow\u2010up, 36 (57%) patients remained recurrence\u2010free off\u2010AAD. Of the 25 patients experiencing recurrence, 21 (84%) were symptomatic. Compared to baseline, follow\u2010up SF\u201036 scores improved significantly in many measures. For patients with successful ablation, physical component summary (PCS) and mental component summary (MCS) demonstrated substantial improvement (MCS: 64.2 \u00b1 22.3 to 70.1 \u00b1 18.6 [P = 0.041]; PCS: 62.6 \u00b1 18.4 to 70.0 \u00b1 14.4 [P = 0.032]). Postablation exercise study in recurrence\u2010free patients showed significant reduction in resting and peak heart rate (75 \u00b1 11 vs. 90 \u00b1 17 and 132 \u00b1 20 vs. 154.5 \u00b1 36, respectively, P &lt; 0.001), increase in peak oxygen pulse (13.4 \u00b1 3 vs. 18.9 \u00b1 16 mL\/beat, \u03945.5 \u00b1 15, P = 0.001), peak VO<jats:sub>2<\/jats:sub>\/kg (19.7 \u00b1 5 to 23.4 \u00b1 13 mL\/kg\/min [\u0394 3.7 \u00b1 10, P = 0.043]), and corresponding MET (5.6 \u00b1 1 to 6.7 \u00b1 4 [\u03941.1 \u00b1 3, P = 0.03]). No improvement was observed in patients with failed procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Successful ablation improves exercise performance and QoL in asymptomatic LSP\u2010AF patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12467","type":"journal-article","created":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T17:07:48Z","timestamp":1401988068000},"page":"1057-1064","source":"Crossref","is-referenced-by-count":84,"title":["Catheter Ablation of Asymptomatic Longstanding Persistent Atrial Fibrillation: Impact on Quality of Life, Exercise Performance, Arrhythmia Perception, and Arrhythmia\u2010Free Survival"],"prefix":"10.1111","volume":"25","author":[{"given":"SANGHAMITRA","family":"MOHANTY","sequence":"first","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center, Austin  Texas USA"},{"name":"College of Natural Sciences University of Texas at Austin  Texas 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