{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:52:49Z","timestamp":1789203169355,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,9,14]],"date-time":"2014-09-14T00:00:00Z","timestamp":1410652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>PVI with nMARQ\u2122<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Simultaneous multipolar ablation catheters have been proposed to simplify pulmonary vein isolation (PVI) in paroxysmal atrial fibrillation (AF). Recently, a new multipolar irrigated radiofrequency (RF) ablation catheter (nMARQ\u2122, Biosense Webster Inc., Diamond Bar, CA, USA) combining both 3\u2010dimensional electroanatomic mapping and multipolar open\u2010irrigated ablation capability has been developed. Aim of our study was to assess feasibility, acute and short\u2010term success and safety of PVI by the use of this new technology with particular regard to the incidence of postablation silent cerebral ischemia (SCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Twenty\u2010five patients (76% males; age 57 \u00b1 13 years) with paroxysmal AF underwent PVI using the nMARQ\u2122 catheter. PVI, confirmed by Lasso catheter mapping, was achieved in 100 out of 102 pulmonary veins (98%) identified, and final PVI was obtained in 24 out of 25 (96%) patients. The overall concordance between Lasso and nMARQ\u2122 signals in demonstrating PVI was 78%. No major procedural complications occurred and no patient suffered SCI, on the basis of cerebral magnetic resonance imaging performed before and after the procedure. Following a 6\u2010month follow\u2010up, 17\/25 (68%) patients remained free from AF without antiarrhythmic drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In our preliminary experience, PVI with nMARQ\u2122 catheter appears to be feasible and safe, without incidence of SCI. Long\u2010term clinical efficacy has to be evaluated in further studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12500","type":"journal-article","created":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T06:56:04Z","timestamp":1406530564000},"page":"1299-1305","source":"Crossref","is-referenced-by-count":28,"title":["Pulmonary Vein Isolation with a New Multipolar Irrigated Radiofrequency Ablation Catheter (nMARQ\u2122): Feasibility, Acute and Short\u2010Term Efficacy, Safety, and Impact on Postablation Silent Cerebral Ischemia"],"prefix":"10.1111","volume":"25","author":[{"given":"MARCO","family":"SCAGLIONE","sequence":"first","affiliation":[{"name":"Cardiology Division Cardinal Guglielmo Massaia Hospital  Asti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DOMENICO","family":"CAPONI","sequence":"additional","affiliation":[{"name":"Cardiology Division Cardinal Guglielmo Massaia Hospital  Asti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MATTEO","family":"ANSELMINO","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medical Sciences University of Turin  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FRANCESCA DI","family":"CLEMENTE","sequence":"additional","affiliation":[{"name":"Cardiology Division Cardinal Guglielmo Massaia Hospital  Asti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ALESSANDRO","family":"BLANDINO","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medical Sciences University of Turin  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FEDERICO","family":"FERRARIS","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medical Sciences University of Turin  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PAOLO DI","family":"DONNA","sequence":"additional","affiliation":[{"name":"Cardiology Division Cardinal Guglielmo Massaia Hospital  Asti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELISA","family":"EBRILLE","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medical Sciences University of Turin  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FRANCK","family":"HALIMI","sequence":"additional","affiliation":[{"name":"Department of Rythmology CMC Parly II Le Chesnay  Le Chesnay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JEAN F.","family":"LECLERCQ","sequence":"additional","affiliation":[{"name":"Department of Rythmology CMC Parly II Le Chesnay  Le Chesnay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"COSTANZA","family":"IUNCO","sequence":"additional","affiliation":[{"name":"Division of Radiology Cardinal Massaia Hospital  Asti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CARLOEUGENIO","family":"VAUDAGNA","sequence":"additional","affiliation":[{"name":"Division of Radiology Cardinal Massaia Hospital  Asti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FEDERICO","family":"CESARANI","sequence":"additional","affiliation":[{"name":"Division of Radiology Cardinal Massaia Hospital  Asti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FIORENZO","family":"GAITA","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medical Sciences University of Turin  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,14]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"2719","article-title":"2012 focused update of the ESC Guidelines for the management of atrial fibrillation. 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