{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T01:10:12Z","timestamp":1775956212140,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,9,16]],"date-time":"2015-09-16T00:00:00Z","timestamp":1442361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Impact of Cryoballoon Ablation on SVC Potentials<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Radiofrequency ablation of the right superior pulmonary vein (RSPV) can lead to inadvertent superior vena cava (SVC) isolation due to the close anatomical proximity. This study aimed to evaluate the impact of PV isolation on SVC potentials with a second\u2010generation cryoballoon.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010one consecutive paroxysmal atrial fibrillation patients who underwent PV isolation exclusively with a 28 mm second\u2010generation cryoballoon and single 3\u2010minute freeze technique were prospectively enrolled. The produced SVC potential conduction delay during the RSPV isolation was prospectively evaluated using circular mapping catheters placed in the SVC throughout the cryoballoon procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Stable SVC potentials were recorded in 28 (90.3%) patients. The produced SVC potential conduction delay during the RSPV isolation was a median of 6.0 (0.5\u20137.6) milliseconds, and &gt;5.0 milliseconds in 16 (57.1%) patients. Among them, the delay had shortened by &gt;5.0 milliseconds in 7 (43.8%) patients within 5 minutes after the RSPV application. The distance between the RSPV ostium and SVC was the sole parameter correlated with the produced delay (R = 0.77, P &lt; 0.0001). For the association between the distance and a produced delay of &gt;5 milliseconds, the area under the curve was 0.896 (95% confidential interval = 0.775\u20131.000). The optimal cutoff point for the distance predicting the occurrence of the conduction delay (&gt;5 milliseconds) was 2.5 mm (sensitivity 83.3%, specificity 81.2%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RSPV isolation with a second\u2010generation cryoballoon could produce an SVC potential conduction delay. The anatomical distance between the RSPV and SVC significantly correlated with the impact.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12816","type":"journal-article","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T09:41:40Z","timestamp":1439890900000},"page":"1321-1326","source":"Crossref","is-referenced-by-count":21,"title":["Impact of Pulmonary Vein Isolation on Superior Vena Cava Potentials With a Second\u2010Generation Cryoballoon"],"prefix":"10.1111","volume":"26","author":[{"given":"NOBORU","family":"ICHIHARA","sequence":"first","affiliation":[{"name":"Cardiovascular Center Tsuchiura Kyodo Hospital  Tsuchiura Ibaraki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHINSUKE","family":"MIYAZAKI","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tsuchiura Kyodo Hospital  Tsuchiura Ibaraki 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