{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T01:58:11Z","timestamp":1787623091532,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,3,9]],"date-time":"2016-03-09T00:00:00Z","timestamp":1457481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Catheter Ablation for \u201cLone\u201d Atrial Fibrillation<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Atrial fibrillation in otherwise healthy young patients has been termed \u201clone\u201d atrial fibrillation (AF). The best treatment choice is still under discussion. The aim of this study was to report on efficacy and safety of catheter ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Among 855 patients referred to our center between 2011 and 2013, 76 (9%) met the diagnostic criteria for lone AF (mean age 45 \u00b1 8 years; mean LA diameter 37 \u00b1 4 mm; paroxysmal AF 82%; persistent AF 18%). The primary endpoint was freedom from any atrial tachycardia after the first ablation; the secondary endpoint was freedom from any atrial tachycardia after the last ablation procedure without antiarrhythmic drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The primary endpoint occurred in 56 patients (74%) after a mean follow\u2010up time of 444 \u00b1 344 days. The secondary endpoint occurred in 73 patients (96%) after a mean of 1.3 ablations\/patient during a follow\u2010up time of 459 \u00b1 366 days. The risk of AF recurrence was not influenced by AF duration or by the type of AF (paroxysmal versus persistent). In a multivariate regression analysis smoking (P = 0.001), first degree atrioventricular block (P = 0.001), and early (&lt; 3 months) AF recurrence (P = 0.001) were independently associated with a higher risk of AF recurrence. Major peri\u2010procedural adverse events did not occur.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Catheter ablation in young healthy patients is highly effective and safe. The outcomes are maintained during long\u2010term follow\u2010up irrespective of preoperative AF duration. Patients with AF recurrence were more likely to smoke, have first degree AV block and early AF recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.12936","type":"journal-article","created":{"date-parts":[[2016,1,22]],"date-time":"2016-01-22T14:10:27Z","timestamp":1453471827000},"page":"536-541","source":"Crossref","is-referenced-by-count":12,"title":["Catheter Ablation for \u201cLone\u201d Atrial Fibrillation: Efficacy and Predictors of Recurrence"],"prefix":"10.1111","volume":"27","author":[{"given":"A.","family":"BUIATTI","sequence":"first","affiliation":[{"name":"Department of Electrophysiology Deutsches Herzzentrum M\u00fcnchen, Technische Universit\u00e4t M\u00fcnchen  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"KAESS","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Deutsches Herzzentrum M\u00fcnchen, Technische Universit\u00e4t M\u00fcnchen  Munich 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