{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:13:00Z","timestamp":1762506780429},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T00:00:00Z","timestamp":1465862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Partial Box Isolation Strategy for Non\u2010Paroxysmal Atrial Fibrillation<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>There are some cases with frequent luminal esophageal temperature (LET) rises despite titrating the radiofrequency energy while creating a linear lesion for the Box isolation of atrial fibrillation (AF). Little is known about the feasibility of redesigning the ablation lines for a modified Box isolation strategy to prevent fatal esophageal injury in those cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Two hundred and seventeen patients who underwent a Box isolation of non\u2010paroxysmal AF were evaluated. We divided them into 2 groups, patients in whom a box lesion set of the entire posterior left atrium had been achieved (complete Box isolation [CBI]; n = 157) and those in whom 2 additional peri\u2010esophageal vertical lines were created at both the right and left ends of the esophagus, and those areas were left with an incomplete isolation when frequent rapid LET rises above 39.0 \u00b0C were observed while creating the floor line (partial Box isolation [PBI]; n = 60). During 20.1 \u00b1 13.9 months of follow\u2010up, the arrhythmia\u2010free rates were 54.1% in the CBI group versus 48.3% in the PBI group (P = 0.62). In the second session, a complete Box isolation was highly achieved even in the PBI group (94.3% vs. 83.3%, respectively; P = 0.17) and after 2 procedures, the arrhythmia\u2010free rates increased to 75.2% vs. 68.3%, respectively (P = 0.34). There was no symptomatic esophageal injury in the PBI group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the case of frequent LET rises while creating the linear lesions for the Box isolation strategy for non\u2010paroxysmal AF, shifting to the PBI strategy was feasible.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13000","type":"journal-article","created":{"date-parts":[[2016,4,27]],"date-time":"2016-04-27T17:24:16Z","timestamp":1461777856000},"page":"897-904","source":"Crossref","is-referenced-by-count":14,"title":["Is It Necessary to Achieve a Complete Box Isolation in the Case of Frequent Esophageal Temperature Rises? Feasibility of Shifting to a Partial Box Isolation Strategy for Patients With Non\u2010Paroxysmal Atrial Fibrillation"],"prefix":"10.1111","volume":"27","author":[{"given":"SATOSHI","family":"HIGUCHI","sequence":"first","affiliation":[{"name":"Heart Rhythm Center, Hayama Heart Center  Shimoyamaguchi, Hayama\u2010cho, Miura\u2010gun Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HIROSHI","family":"SOHARA","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Hayama Heart Center  Shimoyamaguchi, Hayama\u2010cho, Miura\u2010gun Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOSHINORI","family":"NAKAMURA","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Hayama Heart Center  Shimoyamaguchi, Hayama\u2010cho, Miura\u2010gun Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MINORU","family":"IHARA","sequence":"additional","affiliation":[{"name":"Heart Rhythm 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