{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:21:32Z","timestamp":1790720492756,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T00:00:00Z","timestamp":1465862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Spanish Government","award":["TEC2014-52383-C3 (TEC2014-52383-C3-1-R)"],"award-info":[{"award-number":["TEC2014-52383-C3 (TEC2014-52383-C3-1-R)"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Effect of Fat Deposition on the Performance in RF Ablation<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The outcomes of catheter ablation of scar\u2010mediated ventricular tachycardia (VT) remain far from perfect. The presence of fat as a component of the underlying substrate for scar\u2010mediated VT could be relevant since this entity can seriously impede the passage of RF current due to its low electrical conductivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Computer models of RF ablation were built in order to investigate the means by which the spatial heterogeneity of different tissues represented within the ventricular infarct zone, including the viable myocardium, fibrous tissue, and fat, could influence temperature distributions during RF ablation. The results demonstrated that spatial distributions of different tissue types significantly alter the density of electrical current largely as a result of fat impeding the passage of current. However, the thermal lesions appear minimally unaffected by this phenomenon, with variations in depth of \u223c1 mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>While during RF ablation of scar\u2010related ventricular tachycardia differences in tissue characteristics may affect the density of electrical current on a small\u2010scale, overall this does not appear to significantly impact the size of the created thermal lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13006","type":"journal-article","created":{"date-parts":[[2016,5,3]],"date-time":"2016-05-03T11:13:19Z","timestamp":1462273999000},"page":"947-952","source":"Crossref","is-referenced-by-count":15,"title":["Can Fat Deposition After Myocardial Infarction Alter the Performance of RF Catheter Ablation of Scar\u2010Related Ventricular Tachycardia?: Results from a Computer Modeling Study"],"prefix":"10.1111","volume":"27","author":[{"given":"JUAN J.","family":"P\u00c9REZ","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n e Innovaci\u00f3n en Bioingenier\u00eda (Ci2B) Universitat Polit\u00e8cnica de Val\u00e8ncia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANDRE","family":"D'AVILA","sequence":"additional","affiliation":[{"name":"IPAC\u2014Instituto de Pesquisa em Arritmia Cardiaca\u2014Hospital Cardiologico  Florianopolis SC Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ARASH","family":"ARYANA","sequence":"additional","affiliation":[{"name":"Dignity Health Heart and Vascular Institute  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MACARENA","family":"TRUJILLO","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Matem\u00e1tica Pura y Aplicada  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ENRIQUE","family":"BERJANO","sequence":"additional","affiliation":[{"name":"Biomedical Synergy, Electronic Engineering Department Universitat Polit\u00e8cnica de Val\u00e8ncia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002389"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.8.2155"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2005.00324.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.112540"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.03.041"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2532082290"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2009.01.010"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-8807(03)00134-0"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874120701004020047"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12630"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-925X-5-24"},{"key":"e_1_2_6_13_1","unstructured":"HasgallPA 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