{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:16:48Z","timestamp":1762867008113},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T00:00:00Z","timestamp":1482969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Left Atrial Appendage Closure With the New Occlutech\u00ae Device<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Percutaneous left atrial appendage closure (LAAC) is a valuable treatment option for stroke prevention in patients with atrial fibrillation and a HAS\u2010BLED\u2010Score \u22653. Determinants of procedural safety events and neurological outcome of the patients with the Occlutech device (OD) are not established yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Between 2012 and 2016, 30 patients underwent LAAC using the OD. This is a prospective study. Neurological examination and transesophageal echocardiography was performed directly before and after the procedure and after 1, 3, and 12 months. The OC was successfully implanted in 28 of the 30 enrolled patients (93%). Two patients presented a hemodynamic relevant pericardial effusion. A leak &lt;3 mm could be documented direct after implantation in 4 patients. After 3 months, there were only 2\/4 patients with persistent LAA leakage with a maximum leakage of &lt;3 mm. The correct position of the device was confirmed in 27\/28 patients during 3\u2010month follow\u2010up. In 2 patients, there was a thrombus at the OC. In 12 patients, a transoesophageal echocardiography was performed after 12 months. All patients (12\/12) showed a correct placement of the device. None of the patients developed a clinically apparent stroke or died during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this uncontrolled, nonrandomized study, acute and 3\u2010month follow\u2010up success of LAAC using OD was high. No patient showed significant neurological deficits.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13141","type":"journal-article","created":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T13:02:27Z","timestamp":1481115747000},"page":"315-320","source":"Crossref","is-referenced-by-count":19,"title":["Left Atrial Appendage Closure With the New Occlutech\u00ae Device: First in Man Experience and Neurological Outcome"],"prefix":"10.1111","volume":"28","author":[{"given":"BARBARA","family":"BELLMANN","sequence":"first","affiliation":[{"name":"Department of Cardiology, Campus Benjamin Franklin Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"STEFFEN","family":"SCHNUPP","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital Klinikum Coburg  Coburg 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