{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:28:26Z","timestamp":1790252906345,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,14]],"date-time":"2017-01-14T00:00:00Z","timestamp":1484352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Institute for Myocardial Infarction Research (IHF - Institut f\u00fcr Herzinfarktforschung, Ludwigshafen, Germany)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Age\u2010Related Complication Rates in AF Ablation<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Despite a rising demand for catheter ablation (CA) of atrial fibrillation (AF) in an elderly population, complication and success rates are not fully elucidated. We sought to compare complication rates of CA of AF in patients \u226575 versus &lt;75 years of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Patients with symptomatic, drug\u2010refractory AF were prospectively enrolled from January 2007 to 2010 in this multicenter study. A total of 4,449 patients, group 1 \u226575 years and group 2 &lt;75 years (n = 227, age 77.3 \u00b1 2.2 vs. 59.7 \u00b1 9.8 years, 52.0% vs. n = 4,222, 68.9% male, CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>\u2010VASc\u2010Score 3.7 \u00b1 1.0 vs. 1.7 \u00b1 1.2; P &lt; 0.001, respectively), with paroxysmal AF (59.9% in group 1 vs. 63.3% in group 2, P = 0.30), and persistent AF (34.8% in group 1 vs. 29.4% in group 2, P = 0.082) underwent CA of AF. A centralized follow\u2010up was obtained in 4,347 patients by the Institute for Myocardial Infarction Research (IHF, Ludwigshafen). There was a significant difference between periprocedural stroke rates in the elderly versus the younger cohort (1.3% vs. 0.1%, P &lt; 0.01). In\u2010hospital severe nonfatal complications did not differ significantly between the groups (4.4% vs. 2.7%, P = 0.14). Other procedure\u2010related, in\u2010hospital complications were not significantly different. After a mean follow\u2010up of 472 \u00b1 99 days (group 1) and 477 \u00b1 94 days (group 2), no differences were found in complication rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CA of AF in patients \u226575 years is associated with higher in\u2010hospital stroke rates. In a 1\u2010year follow\u2010up, complication rates do not differ between the groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13142","type":"journal-article","created":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T13:42:41Z","timestamp":1481118161000},"page":"258-265","source":"Crossref","is-referenced-by-count":34,"title":["Complication Rates of Catheter Ablation of Atrial Fibrillation in Patients Aged \u226575 Years versus &lt;75 Years\u2014Results from the German Ablation Registry"],"prefix":"10.1111","volume":"28","author":[{"given":"JULIA M.","family":"MOSER","sequence":"first","affiliation":[{"name":"Department of Cardiology\u2014Electrophysiology, University Hospital Hamburg University Heart Center  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STEPHAN","family":"WILLEMS","sequence":"additional","affiliation":[{"name":"Department of Cardiology\u2014Electrophysiology, University Hospital Hamburg University Heart Center  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DIETRICH","family":"ANDRESEN","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Internal Medicine, Evangelisches Krankenhaus Hubertus Charit\u00e9 Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOHANNES","family":"BRACHMANN","sequence":"additional","affiliation":[{"name":"Hospital Klinikum Coburg Teaching Hospital of the University of W\u00fcrzburg  Coburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LARS","family":"ECKARDT","sequence":"additional","affiliation":[{"name":"Division of Electrophysiology, Department of Cardiology and Angiology University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELLEN","family":"HOFFMANN","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Internal Intensive Care Medicine, Heart Center Munich\u2010Bogenhausen Munich Municipal Hospital Group  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KARL\u2010HEINZ","family":"KUCK","sequence":"additional","affiliation":[{"name":"Department of Cardiology Asklepios Klinik St. Georg  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THORSTEN","family":"LEWALTER","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Intensive Care, Peter Osypka Heart Center Munich Hospital Munich\u2010Thalkirchen  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BURGHARD","family":"SCHUMACHER","sequence":"additional","affiliation":[{"name":"2nd Department of Medicine Westpfalz\u2010Klinikum  Kaiserslautern Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STEFAN G.","family":"SPITZER","sequence":"additional","affiliation":[{"name":"Praxisklinik Herz und Gef\u00e4\u00dfe\u2014Teaching Hospital of the Technical University of Dresden  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MATTHIAS","family":"HOCHADEL","sequence":"additional","affiliation":[{"name":"Institute for Myocardial Infarction Research (IHF)  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOCHEN","family":"SENGES","sequence":"additional","affiliation":[{"name":"Institute for Myocardial Infarction Research (IHF)  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BORIS A.","family":"HOFFMANN","sequence":"additional","affiliation":[{"name":"Department of Cardiology II\/Electrophysiology; 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