{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:27:55Z","timestamp":1790738875446,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T00:00:00Z","timestamp":1485734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Pacing Dependency Following TAVI<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Conduction disorders requiring permanent pacemaker (PPM) implantation are a known complication of transcatheter aortic valve implantation (TAVI). Indications for permanent pacing in this setting are still controversial. The study aim was to characterize the natural history of conduction disorders related to TAVI, and to identify predictors for long\u2010term pacing dependency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients who underwent TAVI were included in this prospective observational study. The conduction system was investigated by reviewing 12\u2010lead ECGs during hospitalization and up to 1\u2010year follow\u2010up and by analyzing pacemaker interrogation data. Multivariate analysis was performed in order to identify independent predictors for pacemaker dependency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 110 patients included in the analysis, 38 (34.5%) underwent PPM implantation. Of those, 26 (68.4%) had a long\u2010term pacing dependency (required PPM), while 12 (31.6%) did not (not\u2010required PPM). Logistic regression revealed that baseline RBBB (P = 0.01, OR = 18.0), baseline PR interval (P = 0.019, OR = 1.14), post\u2010TAVI PR interval and the change in PR interval from baseline (P &lt; 0.001 for both, OR = 1.17 for each 10 milliseconds increment) were independent predictors for long\u2010term pacing dependency. A PR interval increment of greater than 28 milliseconds had the best accuracy in predicting pacemaker dependency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Increased pre\u2010 and postprocedural PR intervals and pre\u2010existing RBBB are reliable predictors for long\u2010term PPM dependency, while left bundle branch block or QRS width are misleading factors. Our study suggests that the decision for implanting PPM after TAVI should be based mostly on the prolongation of the PR interval.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13147","type":"journal-article","created":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T06:08:50Z","timestamp":1481522930000},"page":"216-223","source":"Crossref","is-referenced-by-count":43,"title":["Electrocardiographic Predictors of Long\u2010Term Cardiac Pacing Dependency Following Transcatheter Aortic Valve Implantation"],"prefix":"10.1111","volume":"28","author":[{"given":"SIVAN","family":"NAVEH","sequence":"first","affiliation":[{"name":"The Heart Institute Hadassah Hebrew University Medical Center  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GIDON Y.","family":"PERLMAN","sequence":"additional","affiliation":[{"name":"The Heart Institute Hadassah Hebrew University Medical Center  Jerusalem 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