{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:20:01Z","timestamp":1790695201833,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,3]],"date-time":"2017-11-03T00:00:00Z","timestamp":1509667200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Right ventricular (RV)\u2010scar related ventricular tachycardia (VT) is often due to arrhythmogenic right ventricular cardiomyopathy\/dysplasia (ARVC\/D) or cardiac sarcoidosis (CS), but some patients whose clinical course has not been described do not fulfill diagnostic criteria for these diseases. We sought to characterize the electrophysiologic substrate and catheter ablation outcomes of such patients, termed RV cardiomyopathy of unknown source (RCUS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Data of 100 consecutive patients who presented with RV cardiomyopathy and\/or RV\u2010related VT for ablation were reviewed (51 ARVC\/D, 22 CS; 27 RCUS). Compared to ARVC\/D, RCUS patients were older (P\u00a0=\u00a00.001), less commonly had RV dilatation (P\u00a0=\u00a00.001) or dysfunction (P\u00a0=\u00a00.01) and fragmented QRS, parietal block, and T\u2010wave inversion. Compared to CS, R\u2010CUS patients had less severe LV dysfunction. Extent and distribution of endocardial\/epicardial scar and inducible VTs in RCUS patients were comparable with ARVC\/D and CS patients. At a median follow\u2010up of 23 months, RCUS patients had more favorable VT\u2010free survival (RCUS 71%, ARVC\/D 60%, CS 41%, P\u00a0=\u00a00.03) and survival free of death or cardiac transplant (RCUS 92%, ARVC\/D 92%, CS 62%, P\u00a0=\u00a00.01). No RCUS patients developed new criteria for ARVC\/D or CS in follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Up to one\u2010third of patients with RV scar\u2010related VT are not classifiable as ARVC\/D or CS. These patients had a somewhat better prognosis than ARVC\/D or sarcoid and did not develop evidence of these diseases during the initial 2 years of follow\u2010up. The extent to which this population comprises mild ARVC\/D, CS, or other diseases is not clear.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13346","type":"journal-article","created":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T14:26:44Z","timestamp":1506004004000},"page":"79-89","source":"Crossref","is-referenced-by-count":16,"title":["Right ventricular scar\u2010related ventricular tachycardia in nonischemic cardiomyopathy: Electrophysiological characteristics, mapping, and ablation of underlying heart disease"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5643-5076","authenticated-orcid":false,"given":"Saurabh","family":"Kumar","sequence":"first","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"},{"name":"Department of Cardiology, Westmead Hospital University of Sydney  New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2296-4631","authenticated-orcid":false,"given":"Samuel H.","family":"Baldinger","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"},{"name":"Bern University Hospital and University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Kapur","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Romero","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"},{"name":"Montefiore Medical Center, Albert Einstein College of Medicine Montefiore\u2010Einstein Center for Heart &amp; Vascular Care  Bronx NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishaki K.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saagar","family":"Mahida","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"},{"name":"Liverpool Heart and Chest Hospital  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Fujii","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha B.","family":"Tedrow","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William G.","family":"Stevenson","sequence":"additional","affiliation":[{"name":"Arrhythmia Service, Cardiovascular Division Brigham and Women's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.15420\/AER.2016.4.3"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.08.862"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00292-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002145"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000145154.02436.90"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01516.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.840827"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.03.043"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12285"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12202"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000142293.60725.18"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.01.017"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1542-474X.2003.08312.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12246"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.12.009"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.05.017"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01462.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000030187.39852.A7"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.01028.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1989.tb05032.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12858"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.919530"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.044"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.08.014"},{"key":"e_1_2_6_26_1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s00399-012-0180-3","article-title":"The right heart in athletes. 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