{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T02:38:31Z","timestamp":1785033511871,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T00:00:00Z","timestamp":1511222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Although noninferiority of cryoballoon ablation (CBA) and radiofrequency catheter ablation for antral pulmonary vein isolation (APVI) has been reported in patients with paroxysmal atrial fibrillation (PAF), it is not clear whether contact force sensing (CF\u2010RFA) and CBA with the second\u2010generation catheter have similar procedural costs and long\u2010term outcomes. The objective of this study is to compare the long\u2010term efficacy and cost implications of CBA and CF\u2010RFA in patients with PAF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>A first APVI was performed in 146 consecutive patients (age: 63\u00a0\u00b1\u00a010 years, men: 95 [65%], left atrial diameter: 42\u00a0\u00b1\u00a06\u00a0mm) with PAF using CBA (71) or CF\u2010RFA (75). Clinical outcomes and procedural costs were compared. The mean procedure time was significantly shorter with CBA than with CF\u2010RFA (98\u00a0\u00b1\u00a039\u00a0vs. 158\u00a0\u00b1\u00a047\u00a0minutes, P\u00a0&lt;\u00a00.0001). Despite a higher equipment cost in the CBA than the CF\u2010RFA group, the total procedure cost was similar between the two groups (P\u00a0=\u00a00.26), primarily driven by a shorter procedure duration that resulted in a lower anesthesia cost. At 25\u00a0\u00b1\u00a05 months after a single ablation procedure, 51 patients (72%) in the CBA, and 55 patients (73%) in the CF\u2010RFA groups remained free from atrial arrhythmias without antiarrhythmic drug therapy (P\u00a0=\u00a00.84).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The procedure duration was approximately 60 minutes shorter with CBA than CF\u2010RFA. The procedural costs were similar with both approaches. At 2 years after a single procedure, CBA and CF\u2010RFA have similar single\u2010procedure efficacies of 72\u201373%.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13378","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T06:22:41Z","timestamp":1508998961000},"page":"284-290","source":"Crossref","is-referenced-by-count":19,"title":["Ablation of paroxysmal atrial fibrillation using a second\u2010generation cryoballoon catheter or contact\u2010force sensing radiofrequency ablation catheter: A comparison of costs and long\u2010term clinical outcomes"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1879-4131","authenticated-orcid":false,"given":"Miki","family":"Yokokawa","sequence":"first","affiliation":[{"name":"Cardiac Arrhythmia Service, Division of Cardiovascular Medicine University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aman","family":"Chugh","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Service, Division of Cardiovascular Medicine University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Latchamsetty","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Service, Division of Cardiovascular Medicine University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Ghanbari","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Service, Division of Cardiovascular Medicine University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Crawford","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Service, Division of Cardiovascular Medicine University of Michigan  Ann Arbor MI 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Cardiovascular Medicine University of Michigan  Ann Arbor MI 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