{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T01:00:32Z","timestamp":1776214832131,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,15]],"date-time":"2018-01-15T00:00:00Z","timestamp":1515974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We aimed to compare arrhythmia recurrence rates after second\u2010generation cryoballoon (CB\u2010Adv) ablation and radiofrequency (RF) ablation in patients with symptomatic persistent atrial fibrillation (AF) and left atrial (LA) enlargement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Persistent AF patients with LA enlargement were compared using a propensity\u2010score\u2010matching algorithm, and 111 patients treated with CB\u2010Adv ablation and 111 patients treated with RF ablation were selected. The primary endpoint was the first documented &gt;30\u2010second arrhythmia recurrence after a 3\u2010month blanking period. Median LA area was comparable between the RF and CB\u2010Adv groups (24.2 vs. 24.0\u00a0cm<jats:sup>2<\/jats:sup>, P\u00a0=\u00a00.49). In addition to pulmonary vein isolation, roof lines (RLs) with bidirectional conduction block were created in 48 patients in the CB\u2010Adv group and 49 patients in the RF group. Midterm outcome after single procedure is characterized by arrhythmia recurrences in 47 patients in the RF group and 32 patients in the CB\u2010Adv group (P\u00a0=\u00a00.20). There were no differences in the number of AF recurrences in the two groups (38 vs. 32, P\u00a0=\u00a00.66), but there were more instances of LA tachycardia (LAT) in the RF group than in the CB\u2010Adv group (11 vs. 0, P\u00a0&lt;\u00a00.01). LAT recurrence in RF patients was associated with RL creation (9 with vs. 2 without, P\u00a0&lt;\u00a00.01). Among patients in whom a RL was created, arrhythmia\u2010free survival was lower in the RF group than in the CB\u2010Adv group (44.9% vs. 79.2%, P\u00a0&lt;\u00a00.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Arrhythmia recurrence rates in the two groups during midterm follow\u2010up were comparable. RL creation during CB\u2010Adv ablation resulted in acceptable outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13402","type":"journal-article","created":{"date-parts":[[2017,12,11]],"date-time":"2017-12-11T12:12:55Z","timestamp":1512994375000},"page":"375-384","source":"Crossref","is-referenced-by-count":24,"title":["Ice or fire? Comparison of second\u2010generation cryoballoon ablation and radiofrequency ablation in patients with symptomatic persistent atrial fibrillation and an enlarged left atrium"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2379-5443","authenticated-orcid":false,"given":"Ersan","family":"Akkaya","sequence":"first","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Berkowitsch","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergej","family":"Zaltsberg","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald","family":"Greiss","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian W.","family":"Hamm","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"},{"name":"Medicinal Clinic I Justus\u2010Liebig University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Sperzel","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Neumann","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malte","family":"Kuniss","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kerckhoff Heart Center  Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.04.021"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2016.12.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-16-1334"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12695"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu350"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus027"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.10.005"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.07.003"},{"key":"e_1_2_7_10_1","article-title":"Cryoballoon ablation of persistent atrial fibrillation: Feasibility and safety of left atrial roof ablation with generation of conduction block in addition to antral pulmonary vein isolation","volume":"146","author":"Kuniss M","year":"2016","journal-title":"Europace"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.803650"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.03.019"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.07.016"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu068"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euq403"},{"key":"e_1_2_7_16_1","first-page":"82","article-title":"Impact of contact force technology on reducing the recurrence and major complications of atrial fibrillation ablation: A systematic review and meta\u2010analysis","volume":"17","author":"Zhou X","year":"2017","journal-title":"Anatol J Cardiol"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu162"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.12.002"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1408288"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.05.022"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12423"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eul077"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.924878"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12288"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.05.022"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.11.012"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.13402","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.13402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T22:12:35Z","timestamp":1695679955000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.13402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,15]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/jce.13402"],"URL":"https:\/\/doi.org\/10.1111\/jce.13402","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,15]]}}}