{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:25:18Z","timestamp":1740137118376,"version":"3.37.3"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T00:00:00Z","timestamp":1515110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Grant-in-Aid for Scientific Research on Innovative Areas","award":["22136011A02"],"award-info":[{"award-number":["22136011A02"]}]},{"name":"Grant-in-Aid for Scientific Research","award":["24591086"],"award-info":[{"award-number":["24591086"]}]},{"name":"MEXT of Japan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Verapamil\u2010sensitive idiopathic left ventricular tachycardia (verapamil\u2010ILVT) is thought to be due to a reentry within the LV fascicular system. Radiofrequency catheter ablation (RFCA) is effective for elimination of the VT; however, a long\u2010term prognosis of patients with verapamil\u2010ILVT is still unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Eighty consecutive verapamil\u2010ILVT patients (62 men, 31\u00a0\u00b1\u00a012 years of age, LVEF: 65\u00a0\u00b1\u00a04%) were enrolled. Seventy\u2010six (95%) cases of VT involved right bundle branch block and left axis deviation. We retrospectively analyzed changes in the QRS duration (\u0394QRS\u2010d) and QRS axis (\u0394QRS\u2010axis) during follow\u2010up and compared them with recurrence of VT. During a mean follow\u2010up period of 10\u00a0years (2\u201332\u00a0years), no sudden death or heart failure occurred. Fifty\u2010one (64%) patients underwent RFCA, and 46 (90%) of them had no VT without any medication after RFCA. The \u0394QRS\u2010d (16\u00a0\u00b1\u00a02 vs. 8\u00a0\u00b1\u00a01\u00a0ms, P\u00a0=\u00a00.24) and \u0394QRS\u2010axis (20\u00a0\u00b1\u00a04 vs. 4\u00a0\u00b1\u00a03 degrees, P\u00a0=\u00a00.23) were not different in patients with no VT (VT[\u2013]) and those with recurrence of VT (VT[+]). However, in the remaining 29 patients without RFCA, VT was spontaneously eliminated in 16 patients. The \u0394QRS\u2010d (30\u00a0\u00b1\u00a06 vs. 6\u00a0\u00b1\u00a01\u00a0ms, P\u00a0=\u00a00.002) and \u0394QRS\u2010axis (23\u00a0\u00b1\u00a04 vs. 5\u00a0\u00b1\u00a02\u00a0degrees, P\u00a0=\u00a00.001) were significantly larger in VT(\u2013) patients compared to VT(+) patients during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Some verapamil\u2010ILVT patients who show QRS morphology changes over the follow\u2010up period may become free from VT without any invasive or pharmacological treatments, suggesting that further altered LV fascicular conduction might eliminate the reentry of verapamil\u2010ILVT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13403","type":"journal-article","created":{"date-parts":[[2017,12,11]],"date-time":"2017-12-11T12:12:58Z","timestamp":1512994378000},"page":"446-455","source":"Crossref","is-referenced-by-count":0,"title":["Change in QRS morphology as a marker of spontaneous elimination in verapamil\u2010sensitive idiopathic left ventricular tachycardia"],"prefix":"10.1111","volume":"29","author":[{"given":"Hiroshi","family":"Kawakami","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5590-7388","authenticated-orcid":false,"given":"Takeshi","family":"Aiba","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Ishibashi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikutaro","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Wada","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Kamakura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1728-0240","authenticated-orcid":false,"given":"Koji","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Okamura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nagase","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Noda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Kokubo","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"Kamakura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kengo","family":"Kusano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.46.6.679"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90574-X"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90077-2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.77.3.560"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)91211-8"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1995.tb06965.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00247-7"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.18.2408"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00780-4"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2001.00333.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01117-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0402.102663"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:JICE.0000042352.86366.fa"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2012.02312.x"},{"key":"e_1_2_7_16_1","first-page":"1443","article-title":"Catheter ablation of fascicular ventricular tachycardia: Long\u2010term clinical outcomes and mechanisms of recurrence","volume":"8","author":"Liu Y","year":"2015","journal-title":"Circulation"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)00324-J"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.118273"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2012.02377.x"},{"key":"e_1_2_7_20_1","first-page":"657","volume-title":"Cardiac Electrophysiology: From Cell to Bedside","author":"Lerman BB","year":"2009"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.6.2054"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eupc.2004.12.011"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.01023.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2005.06.009"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2011.03044.x"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.13403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.13403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T22:12:50Z","timestamp":1695679970000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.13403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,5]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/jce.13403"],"URL":"https:\/\/doi.org\/10.1111\/jce.13403","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"type":"print","value":"1045-3873"},{"type":"electronic","value":"1540-8167"}],"subject":[],"published":{"date-parts":[[2018,1,5]]}}}