{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:08:41Z","timestamp":1791410921365,"version":"4.3.3"},"reference-count":11,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,5,21]],"date-time":"2018-05-21T00:00:00Z","timestamp":1526860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Pericardial effusion\/tamponade (PE\/PT) is a rare but serious complication following left atrial appendage closure (LAAC). It may be speculated that LAA contraction during sinus rhythm (SR) exerts mechanical force on the device that eventually leads to PE. We sought to determine the incidence and predictors of PE following LAAC using Watchman with special emphasis on the underlying heart rhythm during implant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>From 47 centers in 13 European countries 1,020 patients underwent LAAC and data on baseline rhythm were available from 1,010 patients (mean age 73 \u00b1 9 years, 60% male, median CHA2DS2\u2010VASc\u00a0=\u00a04). Data were collected via electronic case report forms. A Cox proportional hazard model was calculated adjusting for multiple variables: age, gender, number of recaptures, and device oversizing. During implant, 41% and 59% of patients were in SR and atrial fibrillation (AF), respectively. PE\/PT rate was significantly lower in patients implanted during AF at day 30 postimplant (n\u00a0=\u00a01; 0.2% vs. n\u00a0=\u00a06; 1.5%; P\u00a0=\u00a00.02). No PE requiring intervention occurred in the AF group compared to 5 events (1.2%) in the SR group (P\u00a0=\u00a00.01). While univariate analysis identified SR and gender as predictors for PE\/tamponade, multivariate analysis only showed a statistical trend for both variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The overall incidence of PE\/PT was very low after LAAC using Watchman. Although SR was not identified as an independent predictor of PE\/PT, all events requiring intervention occurred in patients with SR. It may be advisable to perform an extended echocardiographic follow\u2010up in that patient population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13626","type":"journal-article","created":{"date-parts":[[2018,5,3]],"date-time":"2018-05-03T10:02:31Z","timestamp":1525341751000},"page":"973-978","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Incidence of pericardial effusion after left atrial appendage closure: The impact of underlying heart rhythm\u2014Data from the EWOLUTION study"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5347-9906","authenticated-orcid":false,"given":"Boris","family":"Schmidt","sequence":"first","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB)  Frankfurt\u00a0Am\u00a0Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy R.","family":"Betts","sequence":"additional","affiliation":[{"name":"John Radcliffe Hospital, Cardiology  Oxford United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horst","family":"Sievert","sequence":"additional","affiliation":[{"name":"CardioVascular Center Frankfurt, Cardiology  Frankfurt Am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin W.","family":"Bergmann","sequence":"additional","affiliation":[{"name":"Cardiologicum Hamburg  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Kische","sequence":"additional","affiliation":[{"name":"Vivantes Klinikum Friedrichshain, Cardiology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeny","family":"Pokushalov","sequence":"additional","affiliation":[{"name":"State Research Institute of Circulation Pathology, Cardiology  Novosibirsk Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schmitz","sequence":"additional","affiliation":[{"name":"Elisabeth Krankenhaus Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Meincke","sequence":"additional","affiliation":[{"name":"Asklepios Klinik St Georg, Cardiology  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizio","family":"Mazzone","sequence":"additional","affiliation":[{"name":"Ospedale San Raffaele  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth M.","family":"Stein","sequence":"additional","affiliation":[{"name":"Boston Scientific  Arden Hills MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fcseyin","family":"Ince","sequence":"additional","affiliation":[{"name":"Vivantes Klinikum am Urban, Cardiology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas V. A.","family":"Boersma","sequence":"additional","affiliation":[{"name":"St Antonius Hospital, Department of Cardiology Nieuwegein, Netherlands\/PI Cardiology, AMC  Amsterdam Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61343-X"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.976449"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.029"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.82.5.547"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.02.005"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26358"},{"key":"e_1_2_7_8_1","first-page":"ehv730","article-title":"Implant success and safety of left atrial appendage closure with the WATCHMAN device: Peri\u2010procedural outcomes from the EWOLUTION registry","author":"Boersma LVA","year":"2016","journal-title":"Eur Heart J"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.06.034"},{"key":"e_1_2_7_10_1","first-page":"4","article-title":"Percutaneous left atrial appendage occlusion\u202f: The Munich consensus document on definitions, endpoints and data collection requirements for clinical studies","volume":"19","author":"Tzikas A","year":"2017","journal-title":"Europace"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.004747"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.10.024"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.13626","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.13626","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T01:19:53Z","timestamp":1694999993000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.13626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,21]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1111\/jce.13626"],"URL":"https:\/\/doi.org\/10.1111\/jce.13626","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,21]]},"assertion":[{"value":"2018-01-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}