{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T17:26:01Z","timestamp":1781803561182,"version":"3.54.5"},"reference-count":47,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T00:00:00Z","timestamp":1540771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ablation strategies have been developed to improve outcomes in patients with persistent atrial fibrillation (PsAF). However, the impact of atrial fibrillation (AF) termination on late AF recurrence is not well known. The aim of our study was to evaluate the impact of AF termination to atrial tachycardia (AT) or sinus rhythm (SR) during catheter ablation on late AF recurrence after the 3\u2010month blanking period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>We prospectively recruited 140 patients (mean age: 58.5\u2009\u00b1\u200912.3 years old, 74.3% males) with uninterrupted PsAF of a mean duration of 3.7 months. Pulmonary vein antral isolation (PVAI) was the first ablation step, and if AF did not terminate (to SR or AT), we ablated low\u2010voltage areas less than 0.4\u2009mV with specific electrogram characteristics. We successfully converted AF to AT or SR in 56 patients (40%) during PVAI (<jats:italic>n<\/jats:italic>\u2009=\u200924) or low\u2010voltage ablation (\n<jats:italic>n<\/jats:italic>\u2009=\u200932). The remaining 84 patients (60%) were electrically cardioverted to SR at the end of the procedure. One hundred patients (71.4%) maintained SR after a single procedure during a mean follow\u2010up of 21.1\u2009\u00b1\u20090.8 months. Of the 56 patients with AF termination, 46 (82.1%) had no recurrence, while in the group of 84 patients without AF termination, 54 patients (64.3%) remained in SR (\n<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ablation of PVAI and specific electrograms in low\u2010voltage areas less than 0.4\u2009mV can lead to encouraging outcomes with a low recurrence rate as well as a lower need for redo procedures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13763","type":"journal-article","created":{"date-parts":[[2018,10,6]],"date-time":"2018-10-06T03:46:32Z","timestamp":1538797592000},"page":"47-57","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Targeted ablation of specific electrogram patterns in low\u2010voltage areas after pulmonary vein antral isolation in persistent atrial fibrillation: Termination to an organized rhythm reduces atrial fibrillation recurrence"],"prefix":"10.1111","volume":"30","author":[{"given":"Michael","family":"Efremidis","sequence":"first","affiliation":[{"name":"Laboratory of Cardiac Electrophysiology Second Department of Cardiology \u201cEvangelismos\u201d General Hospital of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Vlachos","sequence":"additional","affiliation":[{"name":"Laboratory of Cardiac Electrophysiology Second Department of Cardiology \u201cEvangelismos\u201d General Hospital of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos P.","family":"Letsas","sequence":"additional","affiliation":[{"name":"Laboratory of Cardiac Electrophysiology Second Department of Cardiology \u201cEvangelismos\u201d General Hospital of Athens Athens 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