{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:25:31Z","timestamp":1740137131937,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,1,25]],"date-time":"2019-01-25T00:00:00Z","timestamp":1548374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["#81670309","81270242"],"award-info":[{"award-number":["#81670309","81270242"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>While the left sinus of Valsalva (LSV) is a frequent origin of ventricular arrhythmias (VAs). Uncommonly, VAs with right bundle branch block (RBBB) morphology may be successfully terminated from the LSV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We aimed to investigate the electrocardiographic and electrophysiologic characteristics of VAs with RBBB which were successfully eliminated from the LSV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified patients with VAs successfully ablated from the LSV from January 2014 to December 2017 and compared electrophysiologic characteristics and ablation sites of those VAs with RBBB versus a control group of patients with left bundle branch block morphology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 18 patients with RBBB and predominant \u201cR\u201d waves in the precordial leads. In 12 (66.7%) patients, a small \u201cs\u201d wave in lead V2 and positive \u201cR\u201d in the remaining pericardial leads could be seen. Overall, a single \u201cV\u201d potential was seen in 72.2% of patients in the study group, while discrete potentials were recorded in 80% of the patients in the control group. The majority (88.9%) of the VAs could only be terminated at the nadir of the LSV in the study group. After mean follow\u2010up of 33\u2009\u00b1\u200914 months, 93.8% and 92% were free of VAs after initial ablation in study and control group, respectively (<jats:italic>P<\/jats:italic>\u2009=\u20090.99).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Some VAs with predominant monophasic \u201cR\u201d wave in precordial leads could be terminated from LSV, especially a small \u201cs\u201d wave in lead V2 was recorded. The nadir of LSV is highly successful for RBBB VAs and single electrogram was recorded at the target for most of the cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13845","type":"journal-article","created":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T07:46:35Z","timestamp":1547970395000},"page":"541-549","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ablation of ventricular arrhythmias with predominant monophasic \u201cR\u201d waves in precordial leads from the left sinus of Valsalva: Electrocardiographic and electrophysiologic characteristics"],"prefix":"10.1111","volume":"30","author":[{"given":"Jian\u2010du","family":"Yang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010gang","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gong\u2010bu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiology Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Anzhen Hospital, an affiliate of Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Luo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui\u2010qiang","family":"Wei","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai\u2010yang","family":"Xie","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8608-8899","authenticated-orcid":false,"given":"Jackson J","family":"Liang","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiovascular Division, Hospital of the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5136-3774","authenticated-orcid":false,"given":"Jian","family":"Ma","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Arrhythmia Center, Fuwai Hospital, 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