{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T02:03:42Z","timestamp":1762999422105,"version":"3.37.3"},"reference-count":4,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,29]],"date-time":"2019-01-29T00:00:00Z","timestamp":1548720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01\u2010HL\u201049054"],"award-info":[{"award-number":["R01\u2010HL\u201049054"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cardiac resynchronization therapy (CRT) aims to correct delayed left ventricle (LV) activation resulting from left bundle branch block (LBBB). The source of LV activation delay resides in the septum and\/or anterior LV. LV pacing, timed with intrinsic right bundle branch (RBB) conduction, may restore \u201cphysiological\u201d biventricular activation. This is not assured because LV paced wavefronts themselves propagate unpredictably. Less studied are effects of right ventricle (RV) pacing on LV activation in heart failure (HF) patients with LBBB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>In this case RV pacing pre\u2010excited precisely the region left behind during LV pacing. Consequently, biventricular pacing produced confluent LV depolarization (the patient \u201cresponded\u201d to this with reverse remodeling).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Successful electrical resynchronization requires best combination and timing of paced\/intrinsic wavefront(s). This demands individualization. Sometimes, an RV paced wavefront may be valuable to resynchronization.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.13850","type":"journal-article","created":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T07:46:31Z","timestamp":1547970391000},"page":"769-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pacing prescription for cardiac resynchronization therapy: When RV stimulation matters"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2296-2596","authenticated-orcid":false,"given":"Niraj","family":"Varma","sequence":"first","affiliation":[{"name":"Cardiac Electrophysiology Section, Department of Cardiology, University Hospitals Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja","family":"Ghanem","sequence":"additional","affiliation":[{"name":"Cardiac Bioelectricity Research and Training Center, Biomedical Engineering, Case Western Reserve University Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Jia","sequence":"additional","affiliation":[{"name":"Cardiac Bioelectricity Research and Training Center, Biomedical Engineering, Case Western Reserve University Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,29]]},"reference":[{"key":"e_1_2_3_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2007.00719.x"},{"key":"e_1_2_3_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2005.11.025"},{"key":"e_1_2_3_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2014.09.002"},{"key":"e_1_2_3_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13118"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.13850","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.13850","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.13850","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.13850","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T05:47:25Z","timestamp":1694065645000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.13850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,29]]},"references-count":4,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/jce.13850"],"URL":"https:\/\/doi.org\/10.1111\/jce.13850","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"type":"print","value":"1045-3873"},{"type":"electronic","value":"1540-8167"}],"subject":[],"published":{"date-parts":[[2019,1,29]]},"assertion":[{"value":"2019-01-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}