{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:27:55Z","timestamp":1790738875436,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Several single\u2010center short\u2010term studies have demonstrated the feasibility, safety, and positive clinical outcomes of permanent His bundle pacing (HBP). We performed a retrospective study to evaluate long\u2010term technical and safety performances of HBP in a large population of pacemaker patients from two different centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      The analysis includes 844 patients (345 female, mean age\u2009=\u200975\u2009\u00b1\u20099 years) who underwent successful permanent HBP for pacemaker indications from 2004 to 2016. The main endpoints were long term electrical performances including pacing threshold, sensing, impedance, and freedom from pacing related complications. The pacing indication was AV Block in 348 (41.2%) patients, sinus node disease in 147 (17.4%), any bradycardia indication in patients with atrial fibrillation in 335 (39.7%) patients and need for cardiac resynchronization therapy in 14 (1.7%) patients. Mean pacing capture thresholds and sensed R waves were 1.6\u2009V and 5.8\u2009mV, respectively at implant and 2.0\u2009V and 6.1\u2009mV at chronic follow\u2010up. During the median follow up of 3 years (interquartile range\u2009=\u20091\u20106 years), HBP was free of any complication in 91.6% of patients. In the first 368 patients, HBP was achieved using a deflectable curve delivery system, while in 476 using the fixed curve sheath. A significant difference was found in the thresholds (2.4\u2009\u00b1\u20091.0\u2009V and 1.7\u2009\u00b1\u20091.1\u2009V,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001, respectively) and complications (11.9% and 4.2%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001, respectively) between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Permanent HBP was safe and effective during long\u2010term follow\u2010up. The fixed curved delivery sheath offered significantly better electrical parameters and reliability over time. The results of this multicenter study are consistent with recent studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.14063","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T08:37:27Z","timestamp":1563266247000},"page":"1594-1601","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":144,"title":["Long term performance and safety of His bundle pacing: A multicenter experience"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2673-3918","authenticated-orcid":false,"given":"Francesco","family":"Zanon","sequence":"first","affiliation":[{"name":"Cardiology Department, Arrhythmia and Electrophysiology Unit Santa Maria Della Misericordia Hospital  Rovigo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Abdelrahman","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology 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