{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:29:51Z","timestamp":1762507791265,"version":"3.37.3"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T00:00:00Z","timestamp":1564012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Several studies have revealed that second\u2010generation cryoballoon (CB)\u2010based pulmonary vein (PV) isolation is noninferior to radiofrequency (RF)\u2010based PV isolation for patients with drug\u2010refractory paroxysmal atrial fibrillation (AF). However, electrophysiological differences in repeat ablation remain unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>This study examined electrophysiological differences during the repeat ablation between patients who first underwent RF catheter ablation and CB ablation; PV durability and non\u2010PV AF foci were assessed for these patients. We enrolled 919 and 491 patients who underwent CB ablation (CB group) and RF catheter ablation (RF group), respectively, for paroxysmal AF between January 2013 and June 2017 at our institution. PV isolation using RF ablation involved the left atrium (LA) antrum and part of the LA posterior wall. After 2 years of follow\u2010up, 62 and 80 patients in the CB and RF groups, respectively, underwent repeat ablation. PV reconnections were more frequent in the RF group than in the CB group (left superior PV: 46.2% and 14.5%, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; left inferior PV: 35.0% and 11.2%, \n<jats:italic>P<\/jats:italic>\u2009=\u2009.001; right superior PV: 40.0% and 22.6%, \n<jats:italic>P<\/jats:italic>\u2009=\u2009.031; right inferior PV: 36.2% and 19.4%, \n<jats:italic>P<\/jats:italic>\u2009=\u2009.039; PVs: 39.8% and 16.9%, \n<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). LA AF foci were more frequent in the CB group than in the RF group (27.4% and 7.5%; \n<jats:italic>P<\/jats:italic>\u2009=\u2009.002). Other non\u2010PV foci were prevalent in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Fewer LA\u2010PV reconnections occurred with CB ablation. However, extensive PV isolation may eliminate many LA AF foci.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14065","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T12:29:50Z","timestamp":1563280190000},"page":"1792-1800","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Differences in the electrophysiological findings of repeat ablation between patients who first underwent cryoballoon ablation and radiofrequency catheter ablation for paroxysmal atrial fibrillation"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7027-2613","authenticated-orcid":false,"given":"Yukihiro","family":"Inamura","sequence":"first","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"},{"name":"Heart Rhythm Center Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Nitta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2179-3786","authenticated-orcid":false,"given":"Osamu","family":"Inaba","sequence":"additional","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshikazu","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Ikenouchi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuya","family":"Murata","sequence":"additional","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3804-2332","authenticated-orcid":false,"given":"Tomomasa","family":"Takamiya","sequence":"additional","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Department of Cardiology Japanese Red Cross Saitama Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0335-996X","authenticated-orcid":false,"given":"Yoshihide","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Goya","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenzo","family":"Hirao","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,25]]},"reference":[{"key":"e_1_2_7_1_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391003"},{"key":"e_1_2_7_1_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000027821.55835.00"},{"key":"e_1_2_7_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq079"},{"key":"e_1_2_7_1_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602014"},{"key":"e_1_2_7_1_6_1","first-page":"1163","article-title":"GAP\u2010AF study helps to define optimal approach for atrial fibrillation ablation","volume":"35","author":"Tofield A","year":"2014","journal-title":"Eur Heart J"},{"key":"e_1_2_7_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2010.01773.x"},{"key":"e_1_2_7_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.03.015"},{"key":"e_1_2_7_1_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000374"},{"key":"e_1_2_7_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01703.x"},{"key":"e_1_2_7_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12626"},{"key":"e_1_2_7_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.11.006"},{"key":"e_1_2_7_1_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.003879"},{"key":"e_1_2_7_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13648"},{"key":"e_1_2_7_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13397"},{"key":"e_1_2_7_1_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12681"},{"key":"e_1_2_7_1_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01501.x"},{"key":"e_1_2_7_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.11.012"},{"key":"e_1_2_7_1_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.014092"},{"key":"e_1_2_7_1_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-016-0172-z"},{"key":"e_1_2_7_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.08.028"},{"key":"e_1_2_7_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.05.025"},{"key":"e_1_2_7_1_23_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-17-0734"},{"key":"e_1_2_7_1_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn570"},{"key":"e_1_2_7_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.05.014"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjce.14065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.14065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.14065","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.14065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T23:01:46Z","timestamp":1694041306000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.14065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,25]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/jce.14065"],"URL":"https:\/\/doi.org\/10.1111\/jce.14065","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"type":"print","value":"1045-3873"},{"type":"electronic","value":"1540-8167"}],"subject":[],"published":{"date-parts":[[2019,7,25]]},"assertion":[{"value":"2019-04-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}