{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:56:29Z","timestamp":1761562589634,"version":"3.37.3"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T00:00:00Z","timestamp":1579478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cardiac implantable electronic device transvenous (TV) lead reoperations are projected to increase, and robust economic data are needed to assess the resulting financial impact and the cost\u2010effectiveness of prevention and treatment strategies. This study estimates Medicare costs, and describes patterns of complications, in patients who underwent TV lead reoperation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Medicare data (2010\u20102014) were used to identify patients who underwent TV lead reoperation. Cumulative costs to Medicare, and rates of infection and mechanical complications were calculated from 180 days before, to 180 days after, lead reoperation. Multivariate analysis was used to estimate adjusted costs, and to examine the impact of complications on medical resource use and costs. There were 1691 patients, 63.2% of whom underwent inpatient lead reoperation. Overall, the mean age was 78.2 years, 39.6% were female, and 92.3% were white. The mean cumulative cost was $36\u2009199 (95% confidence interval [CI], $31\u2009864\u2010$40\u2009535) for TV lead repositioning, $27\u2009701 (95% CI, $19\u2009869\u2010$35\u2009534) for repair, and $54\u2009442 (95% CI, $51\u2009651\u2010$57\u2009233) for removal. Underlying infection was associated with increased odds of inpatient reoperation and of lead removal, as well as longer length of stay and higher costs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The economic consequences of TV lead reoperation are substantial. Strategies aimed at reducing reoperation, particularly lead removal, are likely to result in considerable cost offsets.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14337","type":"journal-article","created":{"date-parts":[[2020,1,9]],"date-time":"2020-01-09T04:25:22Z","timestamp":1578543922000},"page":"503-511","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Costs and complications associated with transvenous lead reoperation in cardiac implantable electronic devices"],"prefix":"10.1111","volume":"31","author":[{"given":"Robert I.","family":"Griffiths","sequence":"first","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford UK"},{"name":"Health Economics and Outcomes Research Boston Health Economics Inc.  Boston Massachusetts"},{"name":"Health Economics Center of Excellence Boston Scientific Corporation  Marlborough Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey L.","family":"Amorosi","sequence":"additional","affiliation":[{"name":"Health Economics Center of Excellence Boston Scientific Corporation  Marlborough Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline M.","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Health Economics Center of Excellence Boston Scientific Corporation  Marlborough Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"McBee","sequence":"additional","affiliation":[{"name":"Health Economics and Outcomes Research Boston Health Economics Inc.  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Menzin","sequence":"additional","affiliation":[{"name":"Health Economics and Outcomes Research Boston Health Economics Inc.  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8675-8186","authenticated-orcid":false,"given":"Matthew R.","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Economics &amp; Quality of Life Research Baim Institute for Clinical Research  Boston Massachusetts"},{"name":"Cardiology Division Lahey Hospital and Medical Center  Burlington Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2014-000198"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-014-9913-z"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0000000000000247"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.033"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13300"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004768"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.007691"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.05.007"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13009"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.002813"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.003929"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2010.50"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.7326\/M15-2732"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_6_16_1","unstructured":"United States Department of Labor.Bureau of labor statistics. 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