{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T05:04:33Z","timestamp":1788498273053,"version":"build-2803163510"},"reference-count":55,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T00:00:00Z","timestamp":1580342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004331","name":"Johnson and Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The optimal use of intracardiac echocardiography (ICE) may reduce fluoroscopy time and procedural complications during endocardial ablation of cardiac arrhythmias. Due to limited evidence in this area, we conducted the first systematic literature review and meta\u2010analysis to evaluate outcomes associated with the use of ICE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Studies reporting the use of ICE during ablation procedures vs without ICE were searched using PubMed\/MEDLINE. A meta\u2010analysis was performed on the 19 studies (2186 patients) meeting inclusion criteria, collectively representing a broad range of arrhythmia mechanisms. Use of ICE was associated with significant reductions in fluoroscopy time (Hedges' <jats:italic>g<\/jats:italic> \u22121.06; 95% confidence interval [CI] \u22121.81 to \u22120.32; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), fluoroscopy dose (Hedges' <jats:italic>g<\/jats:italic> \u22121.27; 95% CI \u22121.91 to \u22120.62; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), and procedure time (Hedges' <jats:italic>g<\/jats:italic> \u22120.35; 95% CI \u22120.64 to \u22120.05; <jats:italic>P<\/jats:italic>\u2009=\u2009.02) vs ablation without ICE. A 6.95 minute reduction in fluoroscopy time and a 15.2 minute reduction in procedure time was observed between the ICE vs non\u2010ICE groups. These efficiency gains were not associated with any decreased effectiveness or safety. Sensitivity analyses limiting studies to an atrial fibrillation (AF) only population yielded similar results to the main analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of ICE in the ablation of cardiac arrhythmias is associated with significantly lower fluoroscopy time, fluoroscopy dose, and shorter procedure time vs ablation without ICE. These efficiency improvements did not compromise the clinical effectiveness or safety of the procedure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14367","type":"journal-article","created":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T12:44:19Z","timestamp":1579869859000},"page":"664-673","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":90,"title":["The use of intracardiac echocardiography catheters in endocardial ablation of cardiac arrhythmia: Meta\u2010analysis of efficiency, effectiveness, and safety outcomes"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7210-0671","authenticated-orcid":false,"given":"Masahiko","family":"Goya","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Frame","sequence":"additional","affiliation":[{"name":"Real World Evidence CTI Clinical Trial &amp; Consulting Covington Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry","family":"Gache","sequence":"additional","affiliation":[{"name":"Real World Evidence CTI Clinical Trial &amp; Consulting Covington Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Ichishima","sequence":"additional","affiliation":[{"name":"Medical Affairs Johnson &amp; Johnson K.K. 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