{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T09:20:45Z","timestamp":1782206445662,"version":"3.54.5"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T00:00:00Z","timestamp":1584489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>\u201cCLOSE\u201d\u2010guided pulmonary vein isolation (PVI) is based on contiguous (\u22646\u2009mm) and optimized radiofrequency (RF) ablation lesions (ablation index [AI]\u2009\u2265\u2009400 posteriorly and \u2265\u2009550 anteriorly]. However, the optimal RF power to reach the desired AI is unknown. Therefore we evaluated the efficiency of an ablation strategy using higher power (40\u2009W) during a first \u201cCLOSE\u201d\u2010guided PVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty consecutive patients undergoing \u201cCLOSE\u201d\u2010guided PVI for symptomatic paroxysmal atrial fibrillation were ablated with 40\u2009W (group A). Results were compared with 105 consecutive patients enrolled in the \u201cCLOSE to CURE\u201d\u2010study and were ablated using the same protocol with 35\u2009W (group B).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In group A, ablation was associated with shorter ablation procedure time (91 vs 111\u2009minutes; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), shorter fluoroscopy time (5 vs 11\u2009minutes; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), shorter PVI time (48 vs 64\u2009minutes; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), shorter RF time (20 vs 28\u2009minutes; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), lower RF time per application (22 vs 29\u2009seconds; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), less RF applications (52 vs\u00a058; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and less catheter dislocations (1 vs\u00a02; <jats:italic>P<\/jats:italic>\u2009=\u2009.002). The impedance drop (12\u00a0vs\u00a013\u2009\u03a9; <jats:italic>P<\/jats:italic>\u2009=\u2009.192), first\u2010pass isolation rate (99% vs\u00a093%; <jats:italic>P<\/jats:italic>\u2009=\u2009.141) and acute reconnection rate (6% vs 4%; <jats:italic>P<\/jats:italic>\u2009&gt;\u2009.733) were similar in both groups (groups A and B, respectively). No complications occurred. In group A, a gastroscopy\u2014performed in five patients with esophageal temperature rise more than 42\u00b0C\u2014did not reveal any esophageal lesion. Postprocedural recurrence of atrial tachyarrhythmia at 1 year was not significantly different between both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Using the \u201cCLOSE\u201d\u2010protocol, increased power increases the efficiency of PVI without compromising patients' safety.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14438","type":"journal-article","created":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T06:39:46Z","timestamp":1583735986000},"page":"1091-1098","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Evaluation of higher power delivery during RF pulmonary vein isolation using optimized and contiguous lesions"],"prefix":"10.1111","volume":"31","author":[{"given":"Maria","family":"Kyriakopoulou","sequence":"first","affiliation":[{"name":"Department of Cardiology AZ Sint\u2010Jan Hospital Bruges Belgium"},{"name":"Department of Cardiology Universite Libre de 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Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Almorad","sequence":"additional","affiliation":[{"name":"Department of Cardiology AZ Sint\u2010Jan Hospital Bruges Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Hilfiker","sequence":"additional","affiliation":[{"name":"Department of Cardiology AZ Sint\u2010Jan Hospital Bruges Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Phlips","sequence":"additional","affiliation":[{"name":"Department of Cardiology AZ Sint\u2010Jan Hospital Bruges Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Unger","sequence":"additional","affiliation":[{"name":"Department of Cardiology CHU Saint\u2010Pierre Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Lycke","sequence":"additional","affiliation":[{"name":"Department of Cardiology 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