{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T14:41:24Z","timestamp":1776782484959,"version":"3.51.2"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T00:00:00Z","timestamp":1590710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Systematic data on phrenic nerve palsy (PNP) associated with contemporary balloon ablation techniques (cryoballoon [CBA] vs laser balloon [LBA]) are sparse. We aimed to investigate the incidence, characteristics, and clinical recovery course in patients with PNP who underwent CBA or LBA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>A total of 2433 consecutive patients who underwent balloon\u2010based pulmonary vein isolation (CBA: n\u2009=\u20091720 and LBA: n\u2009=\u2009713) were retrospectively identified. PNP was classified into (a) transient (recovery before discharge) or (b) persistent (within 6 months, 6\u201012 months, and &gt;12 months) according to clinical recovery course. In general, PNP occurred significantly more often in CBA 71\/1720 (4.2%) than LBA 11\/713 (1.5%) (<jats:italic>P<\/jats:italic>\u2009=\u2009.003). The rate of transient PNP was significantly higher in CBA (3.0%, n\u2009=\u200945) than LBA (0.1%, n\u2009=\u20091, <jats:italic>P<\/jats:italic>\u2009=\u2009.004). The rate of persistent PNP did not significantly differ between two groups (CBA: 1.2% vs LBA: 1.4%, <jats:italic>P<\/jats:italic>\u2009=\u2009.89). The rate of persistent PNP which recovered within 6 months was similar (CBA: 17.4% vs LBA 18.2%, <jats:italic>P<\/jats:italic>\u2009=\u20091.000). However, the rates of persistent PNP which recovered within 6 to 12 months (CBA: 2.9% vs LBA 27.3%, <jats:italic>P<\/jats:italic>\u2009=\u2009.0171) and more than 12 months (CBA: 7.3% vs LBA 45.5%, <jats:italic>P<\/jats:italic>\u2009=\u2009.0034) were significantly higher in LBA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PNP occurred more often in CBA than LBA, however, the majority of PNP in CBA was transient whereas the majority of PNP in LBA was persistent. Either balloon technology is not superior in terms of long\u2010term PNP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14567","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T06:01:59Z","timestamp":1589781719000},"page":"1932-1941","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Phrenic nerve injury in atrial fibrillation ablation using balloon catheters: Incidence, characteristics, and clinical recovery course"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0299-362X","authenticated-orcid":false,"given":"Shota","family":"Tohoku","sequence":"first","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7082-9573","authenticated-orcid":false,"given":"Shaojie","family":"Chen","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"},{"name":"Die Sektion Medizin Universit\u00e4t zu L\u00fcbeck  L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Last","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0282-4658","authenticated-orcid":false,"given":"Stefano","family":"Bordignon","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7922-3244","authenticated-orcid":false,"given":"Fabrizio","family":"Bologna","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Trolese","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1379-6557","authenticated-orcid":false,"given":"Simone","family":"Zanchi","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6189-7382","authenticated-orcid":false,"given":"Lorenzo","family":"Bianchini","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); Abteilung f\u00fcr Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus Akademisches Lehrkrankenhaus der Goethe\u2010Universit\u00e4t Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5347-9906","authenticated-orcid":false,"given":"Boris","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA); 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