{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:26:25Z","timestamp":1783542385618,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T00:00:00Z","timestamp":1592956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Operation of auto\u2010threshold testing (ATT) algorithm\u00a0in current dual chamber cardiac devices require temporary shortening of atrio\u2010ventricular (AV) delay to accurately measure evoked potential (capture) after a pacing pulse. Near simultaneous AV pacing causes atrial pressure elevation and may be associated with atrial arrhythmias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We evaluated the prevalence of atrial arrhythmias induced by ATT in Abbott devices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Device clinic records were reviewed at a single center for patients with dual chamber Abbott pacemaker\/ICD. ATT\u2010induced atrial fibrillation (AF)\u00a0cases were defined as new appropriate mode switch episodes while the ATT was operating. The auto\u2010capture test trends were defined as unstable if there were deviations &gt;1\u2009V in capture threshold trend events that did not correlate with routine in\u2010office testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and seventy patients were programmed in dual chamber pacing mode. The ventricular ATT was active in 118 patients and of these 78 had true mode switch episodes. Six patients developed AF during ventricular ATT. Three patients had most recorded atrial arrhythmias in close association with ATT (63%, 66%, 100% vs\u00a02%,9%, 33% in other patients with known prior AF). An unstable auto\u2010capture trend curve was seen in 33 patients (6 showing ATT\u2010induced AF) versus\u00a085 patients with stable auto\u2010capture curve and no ATT\u2010induced AF (<jats:italic>P<\/jats:italic>\u2009=\u2009.0001, the <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> test).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ventricular auto\u2010capture algorithm use is associated with induction of AF in dual chamber Abbott devices with a prevalence of over 5%. AF occur more frequently (18%) in patients with erratic ventricular ATT trend results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14606","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T15:31:38Z","timestamp":1591630298000},"page":"2078-2085","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Proarrhythmic effect of automatic threshold testing algorithm in dual chamber devices"],"prefix":"10.1111","volume":"31","author":[{"given":"Timothy R.","family":"Larsen","sequence":"first","affiliation":[{"name":"Division of Cardiology, Section of Electrophysiology Hunter Holmes McGuire VA Medical Center  Richmond Virginia"},{"name":"Division of Cardiology, Pauley Heart Center Virginia Commonwealth University  Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna","family":"Sargent","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Section of Electrophysiology Hunter Holmes McGuire VA Medical Center  Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith","family":"Moyes","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Section of Electrophysiology Hunter Holmes McGuire VA Medical Center  Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5073-9765","authenticated-orcid":false,"given":"Jose F.","family":"Huizar","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Section of Electrophysiology Hunter Holmes McGuire VA Medical Center  Richmond Virginia"},{"name":"Division of Cardiology, Pauley Heart Center Virginia Commonwealth University  Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex Y.","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Section of Electrophysiology Hunter Holmes McGuire VA Medical Center  Richmond Virginia"},{"name":"Division of Cardiology, Pauley Heart Center Virginia Commonwealth University  Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth A.","family":"Ellenbogen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Pauley Heart Center Virginia Commonwealth University  Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6337-9343","authenticated-orcid":false,"given":"Karoly","family":"Kaszala","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Section of Electrophysiology Hunter Holmes McGuire VA Medical Center  Richmond Virginia"},{"name":"Division of Cardiology, Pauley Heart Center Virginia Commonwealth University  Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euj027"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2000.tb07018.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2001.01055.x"},{"key":"e_1_2_6_5_1","first-page":"S169","article-title":"Atrial fibrillation repeatedly induced by automatic threshold testing","volume":"15","author":"Larsen TR","year":"2018","journal-title":"Heart Rhythm"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/sum058"},{"key":"e_1_2_6_7_1","unstructured":"https:\/\/www.medtronicacademy.com\/features\/ventricular-capture-management-feature. 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