{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:20:03Z","timestamp":1789006803058,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T00:00:00Z","timestamp":1592179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Advanced interatrial block (IAB) on a 12\u2010lead electrocardiogram (ECG) is a predictor of stroke, incident atrial fibrillation (AF), and AF recurrence after catheter ablation. The objective of this study was to determine which features of IAB structural remodeling is associated with left atrium (LA) magnetic resonance imaging structure and function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods\/Results<\/jats:title>\n                    <jats:p>\n                      We included 152 consecutive patients (23% nonparoxysmal AF) who underwent preprocedural ECG and cardiac magnetic resonance (CMR) in sinus rhythm before catheter ablation of AF. IAB was defined as P\u2010wave duration \u2265120\u2009ms, and was considered partial if P\u2010wave was positive and advanced if P\u2010wave had a biphasic morphology in inferior leads. From cine CMR and late gadolinium enhancement, we derived LA maximum and minimum volume indices, strain, LA fibrosis, and LA dyssynchrony. A total of 77 patients (50.7% paroxysmal) had normal P\u2010wave, 52 (34.2%) partial IAB, and 23 (15.1%) advanced IAB. Patients with advanced IAB had significantly higher LA minimum volume index (25.7 vs 19.9\u2009mL\/m\n                      <jats:sup>2<\/jats:sup>\n                      ,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.010), more LA fibrosis (21.9% vs 13.1%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.020), and lower LA maximum strain rate (0.99 vs 1.18,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.007) than those without. Advanced IAB was independently associated with LA (minimum [\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.032] and fibrosis [\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.009]). P\u2010wave duration was also independently associated with LA fibrosis (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009.33;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.049) and LA mechanical dyssynchrony (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20092.01;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.007).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Advanced IAB is associated with larger LA volumes, lower emptying fraction, and more fibrosis. Longer P\u2010wave duration is also associated with more LA fibrosis and higher LA mechanical dyssynchrony.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.14608","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T11:33:16Z","timestamp":1591615996000},"page":"1719-1725","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Association between interatrial block, left atrial fibrosis, and mechanical dyssynchrony: Electrocardiography\u2010magnetic resonance imaging correlation"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3859-1833","authenticated-orcid":false,"given":"Luisa","family":"Ciuffo","sequence":"first","affiliation":[{"name":"Division of Internal Medicine University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanesa","family":"Bru\u00f1a","sequence":"additional","affiliation":[{"name":"Servicio de Cardiolog\u00eda, CIBERCV Hospital Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0289-6229","authenticated-orcid":false,"given":"Manuel","family":"Mart\u00ednez\u2010Sell\u00e9s","sequence":"additional","affiliation":[{"name":"Servicio de Cardiolog\u00eda, CIBERCV Hospital Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"},{"name":"Facultad de Ciencias Biom\u00e9dicas, Universidad Europea Facultad de Medicina, Universidad Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Doria","family":"de Vasconcellos","sequence":"additional","affiliation":[{"name":"Division of Cardiology Johns Hopkins University School of Medicine Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Tao","sequence":"additional","affiliation":[{"name":"Division of Cardiology Johns Hopkins University School of Medicine Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek","family":"Zghaib","sequence":"additional","affiliation":[{"name":"Division of Cardiology Johns Hopkins University School of Medicine Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8369-0259","authenticated-orcid":false,"given":"Saman","family":"Nazarian","sequence":"additional","affiliation":[{"name":"Section for Cardiac Electrophysiology Hospital of the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David D.","family":"Spragg","sequence":"additional","affiliation":[{"name":"Division of Cardiology Johns Hopkins University School of Medicine Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5035-5342","authenticated-orcid":false,"given":"Joseph","family":"Marine","sequence":"additional","affiliation":[{"name":"Division of Cardiology Johns Hopkins University School of Medicine Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7427-6750","authenticated-orcid":false,"given":"Ronald D.","family":"Berger","sequence":"additional","affiliation":[{"name":"Division of Cardiology Johns Hopkins University School of Medicine Baltimore Maryland"},{"name":"Department of Biomedical Engineering Johns Hopkins University School of Medicine Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joao A. 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