{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:08:25Z","timestamp":1787015305166,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T00:00:00Z","timestamp":1593993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81500251"],"award-info":[{"award-number":["81500251"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470457"],"award-info":[{"award-number":["81470457"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Left bundle branch area pacing (LBBAP) was reported to improve cardiac function by correcting complete left bundle branch block (CLBBB). Our study aimed to compare the efficacy of LBBAP and biventricular pacing (BIVP) in heart failure patients with CLBBB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ten patients prospectively underwent LBBAP (LBB\u2010CRT group) and 30 patients received BIVP (BIV\u2010CRT group) were matched using propensity score matching. LBBAP was achieved by the trans\u2010interventricular septum method. Echocardiography, electrocardiogram, NYHA classification, and blood B\u2010type natriuretic peptide concentration were evaluated at preimplantation and at 6\u2010month follow up. CRT response was defined as at least 15% decrease in left ventricular end\u2010systolic volume.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the LBB\u2010CRT group, CLBBB were successfully corrected by LBBAP with no complications. QRS duration (QRSd) significantly decreased after implantation in both groups, and the decrease of QRSd in the LBB\u2010CRT group was significantly greater than that in the BIV\u2010CRT group (60.80\u2009\u00b1\u200920.09\u00a0vs. 33.00\u2009\u00b1\u200921.48\u2009ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.0009). The echocardiographic measurements including left ventricular end\u2010diastolic diameter, left ventricular end\u2010systolic diameter, and left ventricular ejection fraction significantly improved after 6 months in both groups. The response rate was significantly higher in LBB\u2010CRT group than BIV\u2010CRT group (100.00% vs. 63.33%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.038). The percentage of patients in New York Heart Association classification Grades I and II was significantly higher in the LBB\u2010CRT group compared with\u00a0that in the BIV\u2010CRT group (median 1.5 vs. 2.0,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.029) at 6\u2010month follow\u2010up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>It is effective and safe to correct CLBBB with LBBAP in heart failure patients. Compared with BIVP, LBBAP can better optimize electrical synchrony and improve cardiac function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.14628","type":"journal-article","created":{"date-parts":[[2020,6,20]],"date-time":"2020-06-20T08:02:37Z","timestamp":1592640157000},"page":"2068-2077","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":82,"title":["The efficacy of left bundle branch area pacing compared with biventricular pacing in patients with heart failure:\u00a0A\u00a0matched case\u2013control study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2185-4980","authenticated-orcid":false,"given":"Yao","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing 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