{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:21:36Z","timestamp":1790720496501,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T00:00:00Z","timestamp":1595462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Local impedance (LI) at the tip of ablation catheter can be measured using a recently available technology. We aimed to explore target LI measurements at each radiofrequency application (RFA) for creating sufficient ablation lesions during pulmonary vein (PV) isolation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study included 15 consecutive patients scheduled to undergo an initial ablation of paroxysmal atrial fibrillation (AF). Circumferential ablation around both ipsilateral PVs was performed using a 4\u2010mm irrigated ablation catheter with an LI sensor. Point\u2010by\u2010point ablation was used with a 4\u2010mm inter\u2010ablation\u2010point distance. Operators were blinded to LI measurements during the procedure. Creation of sufficient ablation lesions was assessed by the absence of a conduction gap.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After first\u2010pass encircling PV antrum ablation, left atrium to PV conduction remained in 12 of 30 (40%) ipsilateral PVs. Mapping using the minibasket catheter identified 48 ablation points through which the propagation wave entered the PV. At ablation points with a gap, the LI drop during RFA was half that at points without a gap (12\u2009\u00b1\u20097 vs. 23\u2009\u00b1\u200912\u2009\u03a9; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). The generator impedance drop did not differ between ablation points with and without a gap (12\u2009\u00b1\u20097 vs. 14\u2009\u00b1\u200910 \u2009\u03a9; <jats:italic>p<\/jats:italic>\u2009=\u2009.10). An LI drop of 13.4\u2009\u03a9 predicted sufficient lesion formation without a gap with a sensitivity of 0.78, specificity of 0.75, and predictive accuracy of 0.75.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>An LI drop of 13.4\u2009\u03a9 at each RFA under the conditions of a 4\u2010mm inter\u2010ablation\u2010point distance and RFA duration \u226520\u2009s may facilitate creation of sufficient lesions during PV isolation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14678","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T08:26:03Z","timestamp":1594887963000},"page":"2584-2591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Clinical utility of local impedance monitoring during pulmonary vein isolation"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5566-466X","authenticated-orcid":false,"given":"Masaharu","family":"Masuda","sequence":"first","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kanda","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Kurata","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsutoshi","family":"Asai","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Iida","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyonori","family":"Nanto","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Tsujimura","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Uematsu","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Mano","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Kansai Rosai Hospital Cardiovascular Center Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000151289.73085.36"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1992.tb02897.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.10.048"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/joa3.12056"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.001094"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"e005831","DOI":"10.1161\/CIRCEP.117.005831","article-title":"A novel measure of local impedance predicts catheter\u2010tissue contact and lesion formation","volume":"4","author":"Sulkin MS","year":"2018","journal-title":"Circ Arrhythm 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