{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T12:59:59Z","timestamp":1789822799994,"version":"4.0.1"},"reference-count":60,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NIH\/ORWH Building Interdisciplinary Research Caree"],"award-info":[{"award-number":["NIH\/ORWH Building Interdisciplinary Research Caree"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The presentation and optimal management of maternal focal atrial tachycardia (AT) during pregnancy are unknown. The objective of this study is to conduct a comprehensive summary of the existing evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>A systematic review of all reported cases of maternal focal AT during pregnancy was performed. The primary search queried PubMed using the MeSH terms \u201csupraventricular tachycardia\u201d and \u201cpregnancy.\u201d A stepwise ancillary search included article bibliographies, citations listed by the Google internet search engine, and PubMed using the MeSH terms \u201catrial tachycardia\u201d and \u201cpregnancy.\u201d In total, 28 citations that described 32 patients were retrieved. A case from our institution was added. Detailed information was available for 30 patients. Clinical characteristics at presentation included a mean\u2009\u00b1\u2009standard deviation of 28.3\u2009\u00b1\u20095.7 years for maternal age and 24.6\u2009\u00b1\u20097.7 weeks for gestation age. Suspected tachycardia\u2010induced cardiomyopathy was present in 20 of 30 (67%) patients and left ventricular ejection fraction improved in 15 of 15 (100%) patients with follow\u2010up measurements. Medication failure was common. Focal AT resolved spontaneously after delivery in eight of nine\u00a0(89%) patients treated with only medications. Automaticity was suggested by discrete electrograms at sites of origin and lack of reported inducibility and termination with programmed stimulation in all patients who underwent electrophysiology studies. There were nine cases of successful catheter ablation with zero fluoroscopy since 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Automaticity is the dominant mechanism for patients with maternal focal AT during pregnancy. Catheter ablation with zero fluoroscopy is an emerging therapy for medically refractory cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14738","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T15:58:31Z","timestamp":1600703911000},"page":"2982-2997","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Maternal focal atrial tachycardia during pregnancy: A systematic review"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8388-2146","authenticated-orcid":false,"given":"Norman C.","family":"Wang","sequence":"first","affiliation":[{"name":"Heart and Vascular Institute University of Pittsburgh Medical Center  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlita","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Pittsburgh School of Medicine  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