{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:11:40Z","timestamp":1778875900998,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T00:00:00Z","timestamp":1612915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The next\u2010generation Watchman FLX left atrial appendage closure (LAAC) device has: (1) an atraumatic closed distal end, (2) reduced height, (3) a recessed screw hub to decrease device\u2010related thrombus (DRT), (4) two rows of J\u2010shape anchors so redeployment is possible after full recapture, and (5) ability to treat a greater size range of LAA ostia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report, for the first time, the feasibility and safety of intracardiac echocardiography (ICE)\u2010guided Watchman FLX implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single\u2010center prospective registry of atrial fibrillation patients planned for LAAC with the FLX device underwent ICE\u2010guided implantation with conscious sedation. Transesophageal echocardiography (TEE) imaging was done preprocedure (to assess LAA size and exclude thrombus) and at clinical follow\u2010up at 6\u201312 weeks. Clinical outcomes were LAA closure success, complications, leak, or DRT on follow\u2010up TEE and major safety events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 30 patients: age 75\u2009\u00b1\u20098 years, 53% men, CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>\u2010VASc 4.6\u2009\u00b1\u20091.6, and HAS\u2010BLED 3.4\u2009\u00b1\u20091.1. The primary indication was prior bleeding in 60% (72% GI bleeding). The LAA orifice width and length were 22.7\u2009\u00b1\u20093.1 and 25.7\u2009\u00b1\u20095.7\u2009mm, respectively. Technical success was 100% (the first\u2010choice device was used in 28 of 30). Procedure time was less than 30 min in 27 of 30 cases, with 36\u2009\u00b1\u200915\u2009ml contrast used. The final device size was 29.2\u2009\u00b1\u20094.7\u2009mm with 21.6\u2009\u00b1\u20094.5% compression. There were no procedure\u2010related complications. Follow\u2010up TEE at a median 47 days follow\u2010up showed 100% device success with no DRT or peridevice leak \u22655\u2009mm. Major safety events occurred in 6.6% (2\/30).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The Watchman FLX device can be safely implanted with intraprocedural ICE imaging instead of TEE.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14927","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T22:11:33Z","timestamp":1612563093000},"page":"717-725","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Intracardiac echocardiography\u2010guided implantation of the Watchman FLX left atrial appendage closure device"],"prefix":"10.1111","volume":"32","author":[{"given":"Mohit K.","family":"Turagam","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petr","family":"Neuzil","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Homolka Hospital  Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Petru","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Homolka Hospital  Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Hala","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Homolka Hospital  Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas","family":"Mraz","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Homolka Hospital  Prague Czech 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USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5638-4993","authenticated-orcid":false,"given":"Vivek Y.","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Icahn School of Medicine at Mount Sinai  New York New York USA"},{"name":"Department of Cardiovascular Medicine Homolka Hospital  Prague Czech 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