{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:50:56Z","timestamp":1762098656121,"version":"3.37.3"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T00:00:00Z","timestamp":1616025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The success rate after cryoballoon ablation (CB\u2010A) performed for paroxysmal atrial fibrillation (PAF) might be overestimated by traditional noninvasive monitoring techniques. The purpose of this study was to evaluate the mid\u2010term outcome of CB\u2010A in patients with PAF implanted with an implantable loop recorder (ILR) after the procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2017 and March 2019, all patients who underwent CB\u2010A for PAF and who were subsequently implanted with an ILR were retrospectively included. All devices were equipped with remote monitoring. All ILR\u2010documented atrial tachycardia (AT) or AF episodes\u2009\u2265\u20096\u2009min were considered as recurrence; both true and false episodes were collected. A 3\u2010month post\u2010procedural blanking period (BP) was applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 102 patients (77 men, mean age 60.6\u2009\u00b1\u20099.6 years) who underwent pulmonary vein isolation (PVI) by CB\u2010A were included; mean time from first diagnosis of AF to PVI was 51.5\u2009\u00b1\u200946.9 months. Mean follow\u2010up was 29.3\u2009\u00b1\u20098.1 months; at 12\u2010month follow\u2010up, the success rate was 65.7%, while at 2\u2010year follow\u2010up, freedom from AT\/AF recurrences was achieved in 59.3% of the patients. In the follow\u2010up, a total of 4987 ECG strips were analyzed; true\u2010positive episodes were confirmed in 2026 cases (40.6%), whereas 2961 episodes (59.4%) were considered false\u2010positive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with PAF implanted with an ILR, CB\u2010A results in freedom from any AT\/AF recurrence in 65.7% of patients at 12\u2010month follow\u2010up and in 59.3% of patients when evaluated at 2\u2010year. Careful adjudication of all ILR\u2010documented AF episodes is required to avoid misdiagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.14998","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T08:09:22Z","timestamp":1615450162000},"page":"933-940","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Cryoballoon ablation for paroxysmal atrial fibrillation: mid\u2010term outcome evaluated by ECG monitoring with an implantable loop recorder"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7794-6414","authenticated-orcid":false,"given":"Riccardo","family":"Maj","sequence":"first","affiliation":[{"name":"Cardiovascular Department San Gerardo Hospital, ASST\u2010Monza Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"De Ceglia","sequence":"additional","affiliation":[{"name":"Cardiovascular Department San Gerardo Hospital, ASST\u2010Monza Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Piazzi","sequence":"additional","affiliation":[{"name":"Cardiovascular Department San Gerardo Hospital, ASST\u2010Monza Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattia","family":"Pozzi","sequence":"additional","affiliation":[{"name":"Cardiovascular Department San Gerardo Hospital, ASST\u2010Monza Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Montemerlo","sequence":"additional","affiliation":[{"name":"Cardiovascular Department San Gerardo Hospital, ASST\u2010Monza Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirko","family":"Casiraghi","sequence":"additional","affiliation":[{"name":"Cardiovascular Department San Gerardo Hospital, ASST\u2010Monza Monza 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