{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:53:55Z","timestamp":1788447235993,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T00:00:00Z","timestamp":1618531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007497","name":"Biosense Webster","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/100007497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Contact force (CF) guided ablation of paroxysmal atrial fibrillation (PAF) with stable catheter\u2010tissue contact optimizes clinical success and may increase an operator's ability to achieve pulmonary vein isolation (PVI) in a single encirclement. First pass PVI reduces procedure time but the relationship with long term clinical success is not well understood. This study evaluated patient characteristics and procedural details as predictors of 1\u2010year clinical success after PAF ablation, including first pass isolation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive de novo PAF ablations were performed with a porous tip CF catheter in 2017 and 2018. All ablations used wide\u2010area circumferential ablation, with first pass isolation captured separately for the left and right pulmonary veins (PVs). CF was held between 10 and 20\u2009g and the catheter was moved every 10\u201320\u2009s. Radiofrequency energy was set at 40\u201345\u2009W throughout the atrium. Patient characteristics and procedural details were tested for association with clinical success, defined as freedom from recurrent atrial tachyarrhythmia through 1 year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 404 patients were included in the study. Clinical success at 1 year was 86.6%. Achieving first pass isolation on at least one ipsilateral PV pair was the most significant predictor of clinical success (<jats:italic>p<\/jats:italic>\u2009=\u2009.0126). After controlling for first pass isolation, only recurrence within the 90\u2010day blanking period was independently predictive (<jats:italic>p<\/jats:italic>\u2009=\u2009.0015). First pass isolation was not associated with early recurrence (<jats:italic>p<\/jats:italic>\u2009=\u2009.2454).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a real\u2010world setting, first pass isolation was highly predictive of 12\u2010month clinical success after CF\u2010guided ablation in a PAF population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15028","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T05:08:00Z","timestamp":1617772080000},"page":"1814-1821","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Predictors of clinical success after paroxysmal atrial fibrillation catheter ablation"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7466-123X","authenticated-orcid":false,"given":"Jose","family":"Osorio","sequence":"first","affiliation":[{"name":"Arrhythmia Institute at Grandview  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3410-2999","authenticated-orcid":false,"given":"Tina D.","family":"Hunter","sequence":"additional","affiliation":[{"name":"CTI Clinical Trial &amp; Consulting Services  Covington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Rajendra","sequence":"additional","affiliation":[{"name":"Arrhythmia Institute at Grandview  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3681-2321","authenticated-orcid":false,"given":"Paul","family":"Zei","sequence":"additional","affiliation":[{"name":"Brigham And Women's Hospital Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Silverstein","sequence":"additional","affiliation":[{"name":"Mount Carmel Health System  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Morales","sequence":"additional","affiliation":[{"name":"Arrhythmia Institute at Grandview  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.2029"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/POR.S134777"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.072"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-023775"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2016.07.014"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.23297"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux264"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4022\/jafib.2097"},{"key":"e_1_2_9_10_1","article-title":"Abstract 13136: first\u2010pass isolation is associated with durability of pulmonary vein isolation and has impact on atrial fibrillation ablation outcomes","volume":"140","author":"Ninomiya Y","year":"2019","journal-title":"Circulation"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ipej.2019.05.001"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13281"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12933"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux376"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2009.2038791"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14340"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-015-0060-y"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14160"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-019-00639-3"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-17-0421"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2020.11.020"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15028","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.15028","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T19:51:46Z","timestamp":1693425106000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.15028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,16]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/jce.15028"],"URL":"https:\/\/doi.org\/10.1111\/jce.15028","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,16]]},"assertion":[{"value":"2020-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}