{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T21:08:18Z","timestamp":1776287298098,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V109D48\u2010001\u2010MY2\u20102, C19\u2010027"],"award-info":[{"award-number":["V109D48\u2010001\u2010MY2\u20102, C19\u2010027"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Identifying the critical isthmus (CI) in scar\u2010related macroreentrant atrial tachycardia (AT) is challenging, especially for patients with cardiac surgery. We aimed to investigate the electrophysiological characteristics of scar\u2010related macroreentrant ATs in patients with and without cardiac surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective study of 31 patients (mean age 59.4\u2009\u00b1\u20099.81 years old) with scar\u2010related macroreentrant ATs were enrolled for investigation of substrate properties. Patients were categorized into the nonsurgery (<jats:italic>n<\/jats:italic>\u2009=\u200918) and surgery group (<jats:italic>n<\/jats:italic>\u2009=\u200913). The CIs were defined by concealed entrainment, conduction velocity less than 0.3\u2009m\/s, and the presence of local fractionated electrograms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 31 patients, a total of 65 reentrant circuits and 76 CIs were identified on the coherent map<jats:bold>.<\/jats:bold> The scar in the surgical group is larger than the nonsurgical group (18.81\u2009\u00b1\u20099.22 vs. 10.23\u2009\u00b1\u20095.34%, <jats:italic>p<\/jats:italic>\u2009=\u2009.016). The CIs in surgical group have longer CI length (15.27\u2009\u00b1\u20094.89 vs. 11.20\u2009\u00b1\u20092.96\u2009mm, <jats:italic>p<\/jats:italic>\u2009=\u2009.004), slower conduction velocity (0.46\u2009\u00b1\u20090.19 vs. 0.69\u2009\u00b1\u20090.14\u2009m\/s, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), and longer total activation time (45.34\u2009\u00b1\u20099.04 vs. 38.24\u2009\u00b1\u20098.41%, <jats:italic>p<\/jats:italic>\u2009=\u2009.016) than those in the nonsurgical group. After ablation, 93.54% of patients remained in sinus rhythm during a follow\u2010up of 182\u2009\u00b1\u200919 days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The characteristics of the isthmus in macroreentrant AT are diverse, especially for surgical scar\u2010related AT. The identification of CIs can facilitate the successful ablation of scar\u2010related ATs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15034","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T01:22:28Z","timestamp":1617931348000},"page":"1921-1930","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The isthmus characteristics of scar\u2010related macroreentrant atrial tachycardia in patients with and without cardiac surgery"],"prefix":"10.1111","volume":"32","author":[{"given":"Shin\u2010Huei","family":"Liu","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Heart Rhythm Center Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"Institute of Clinical Medicine National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8395-1052","authenticated-orcid":false,"given":"Yenn\u2010Jiang","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Heart Rhythm Center Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"Institute of Clinical Medicine National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po\u2010Tseng","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Heart Rhythm Center Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6722-1826","authenticated-orcid":false,"given":"Jennifer Jeanne","family":"Vicera","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Heart Rhythm Center Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0545-2156","authenticated-orcid":false,"given":"Shih\u2010Lin","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Heart Rhythm Center Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"Institute of Clinical Medicine National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9102-227X","authenticated-orcid":false,"given":"Li\u2010Wei","family":"Lo","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Heart Rhythm Center Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"Institute of Clinical Medicine National Yang Ming Chiao Tung University  Taipei 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Bar\u2010talAB MontagAD Inventor. Iterative coherent mapping of cardiac electrophysiological (EP) activation including scar effects. US Patent 10 842 400 B2. Nov. 24 2020."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2010.02002.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1667065"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.09.147"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.003582"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.117.006019"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(02)73603-9"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.117.006019"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15034","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.15034","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T19:52:15Z","timestamp":1693425135000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.15034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,19]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/jce.15034"],"URL":"https:\/\/doi.org\/10.1111\/jce.15034","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,19]]},"assertion":[{"value":"2020-11-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}